Gilotrif and Lantus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gilotrif (afatinib dimaleate) and Lantus (insulin glargine recombinant). Common drug interactions include diarrhoea among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Gilotrif and Lantus. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Gilotrif?
Gilotrif has active ingredients of afatinib dimaleate. eHealthMe is studying from 6,055 Gilotrif users. Check the latest studies of Gilotrif.
What is Lantus?
Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
18 people who take Gilotrif and Lantus together, and have interactions are studied.

What are the common drug interactions of Gilotrif and Lantus, by gender? *:
female:
- Diarrhoea
- Stomatitis (inflammation of mucous membrane of mouth)
- Nausea (feeling of having an urge to vomit)
- Dehydration (dryness resulting from the removal of water)
- Pruritus (severe itching of the skin)
- Malaise (a feeling of general discomfort or uneasiness)
- Alopecia (absence of hair from areas of the body)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Constipation
- Corneal scar (nullah)
male:
- Diarrhoea
- Stomatitis (inflammation of mucous membrane of mouth)
- Food intolerance (inability to have food)
- Haemorrhage (bleeding)
- Peripheral coldness
- Pigmentation disorder (disturbances of human skin colour)
- Pleural effusion (water on the lungs)
- Surgery
- Haematochezia (passage of stools containing blood)
- Hypersensitivity
What are the common drug interactions of Gilotrif and Lantus, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Diarrhoea
- Stomatitis (inflammation of mucous membrane of mouth)
- Decreased appetite
- Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
- Infection
- Joint swelling
- Pleural effusion (water on the lungs)
- Pneumonia
- Pruritus (severe itching of the skin)
- Pulmonary embolism (blockage of the main artery of the lung)
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 11 people, 61.11%
- Lung Adenocarcinoma (a form of non-small cell lung cancer): 4 people, 22.22%
- Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 16.67%
- High Blood Cholesterol: 1 person, 5.56%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.56%
- Blood Pressure Abnormal: 1 person, 5.56%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 5.56%
- Cancer Pain: 1 person, 5.56%
- Dyspnea (difficult or laboured breathing): 1 person, 5.56%
- Type 1 Diabetes: 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Gilotrif and Lantus?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Gilotrif and Lantus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gilotrif:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lantus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gilotrif and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lantus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on afatinib dimaleate and insulin glargine recombinant (the active ingredients of Gilotrif and Lantus, respectively), and Gilotrif and Lantus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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