Gleevec and Avelox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Avelox (moxifloxacin hydrochloride). Common drug interactions include musculoskeletal stiffness among females and weight decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Gleevec and Avelox. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Gleevec?
Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.
What is Avelox?
Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.
20 people who take Gleevec and Avelox together, and have interactions are studied.

What are the common drug interactions of Gleevec and Avelox, by gender? *:
female:
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Pleural fibrosis (formation of fibrous tissue in lung)
- Polyserositis (general inflammation of serous membranes, with effusion)
- Pyothorax (accumulation of pus in the pleural cavity)
- Pyrexia (fever)
- Rash
- Rash erythematous (redness of the skin)
- Red blood cell sedimentation rate increased
- Renal cyst (kidney cyst)
male:
- Weight decreased
- Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
- Drug hypersensitivity
- Dysgeusia (disorder of the sense of taste)
- Fatigue (feeling of tiredness)
- Large intestine perforation (hole in large intestine)
- Nausea (feeling of having an urge to vomit)
- Weight gain poor
- Anxiety
- Arthralgia (joint pain)
What are the common drug interactions of Gleevec and Avelox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Eye haemorrhage (bleeding in the eye)
- Eye swelling
60+:
- Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
- Renal failure acute (rapid kidney dysfunction)
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Anxiety
- Arthralgia (joint pain)
- Burning sensation
- C-reactive protein increased
- Dry skin
- Erythema (redness of the skin)
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
What are the existing conditions these people have? *
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 12 people, 60.00%
- Pneumonia: 8 people, 40.00%
- Epididymitis (pain in the scrotum or testicle): 7 people, 35.00%
- Oedema (fluid collection in tissue): 5 people, 25.00%
- High Blood Pressure: 5 people, 25.00%
- Urinary Tract Infection: 4 people, 20.00%
- Pleurisy (inflammation of the pleurae, which causes pain when breathing): 3 people, 15.00%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 15.00%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 10.00%
- Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Gleevec and Avelox?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Gleevec and Avelox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gleevec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Avelox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gleevec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avelox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on imatinib mesylate and moxifloxacin hydrochloride (the active ingredients of Gleevec and Avelox, respectively), and Gleevec and Avelox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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