Gleevec and Avonex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Avonex (interferon beta 1a). Common drug interactions include fall among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Gleevec and Avonex. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Gleevec?
Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.
What is Avonex?
Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.
11 people who take Gleevec and Avonex together, and have interactions are studied.

What are the common drug interactions of Gleevec and Avonex, by gender? *:
female:
- Fall
- Gait disturbance
- Hemiparesis (weakness on one side of the body)
- Benign breast neoplasm (benign (non-cancerous) tumours of the breast)
- Cardiac failure congestive
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
- Eye disorder
- General symptom
male:
- Fatigue (feeling of tiredness)
- Muscular weakness (muscle weakness)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Optic neuritis (optic nerve inflammation)
- Fall
- Visual impairment
- Abasia (inability to walk)
- Abdominal pain upper
- Death
- Delusion (a false belief or opinion)
What are the common drug interactions of Gleevec and Avonex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Bipolar disorder (mood disorder)
- Essential hypertension (primary hypertension)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gastrointestinal stromal tumour (a cancer that arises from transformed cells of mesenchymal origin in gastrointestinal tract)
- Hypercholesterolaemia (high levels of cholesterol in the blood)
60+:
- Fall
- Hemiparesis (weakness on one side of the body)
- Diarrhoea
- Epistaxis (bleed from the nose)
- Erythema (redness of the skin)
- Face injury
- Gait disturbance
- Gastrointestinal injury (injury to gastrointestinal tract)
- Hand fracture
- Injection site pain
What are the existing conditions these people have? *
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 27.27%
- Gastrointestinal Stromal Tumor: 2 people, 18.18%
- Leukaemia (blood or bone marrow cancer): 1 person, 9.09%
- Hepatic Cancer Metastatic (liver cancer - metastatic): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Gleevec and Avonex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Gleevec and Avonex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gleevec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Avonex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gleevec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avonex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on imatinib mesylate and interferon beta 1a (the active ingredients of Gleevec and Avonex, respectively), and Gleevec and Avonex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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