Gleevec and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Azithromycin (azithromycin). Common drug interactions include eye haemorrhage among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Gleevec and Azithromycin. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.



On Jul, 06, 2026

31 people who take Gleevec and Azithromycin together, and have interactions are studied.

Gleevec and Azithromycin drug interactions.

What are the common drug interactions of Gleevec and Azithromycin, by gender? *:

female:

  1. Eye haemorrhage (bleeding in the eye)
  2. Gastric perforation (hole in stomach)
  3. Glaucoma (increased fluid pressure in the eye with vision loss)
  4. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  5. Hospitalisation
  6. Hyperbilirubinaemia (excess of bilirubin in the blood)
  7. Pain
  8. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  9. Respiratory disorder (respiratory disease)
  10. Swelling face

male:

  1. Abdominal pain upper
  2. Candidiasis (candidiasis or thrush is a fungal infection)
  3. Lip exfoliation
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Oral pain
  7. Oropharyngeal pain
  8. Pulmonary hypertension (increase in blood pressure in the lung artery)
  9. Pyrexia (fever)
  10. Rhinorrhoea (watery mucus discharge from the nose)

What are the common drug interactions of Gleevec and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Drug intolerance (drug sensitivity)
  2. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  3. Drug ineffective
  4. Cerebral disorder (brain disease)
  5. Burning sensation
  6. Depression

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Chest discomfort
  3. Dyspepsia (indigestion)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Pulmonary hypertension (increase in blood pressure in the lung artery)
  6. Sneezing
  7. Syncope (loss of consciousness with an inability to maintain postural tone)

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fall
  3. Cardiac disorder
  4. Influenza
  5. Oedema peripheral (superficial swelling)
  6. Pulmonary function test decreased
  7. Urinary retention (the inability to completely or partially empty the bladder)
  8. Abdominal discomfort
  9. Anaemia (lack of blood)
  10. Anxiety

50-59:

  1. Back pain
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Muscle contractions involuntary (uncontrolled muscle contraction)
  4. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  5. Vomiting
  6. Aspartate aminotransferase increased
  7. Blood creatine phosphokinase increased
  8. Muscle cramp (painful sensation caused by muscle contraction)
  9. Muscle spasms (muscle contraction)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Candidiasis (candidiasis or thrush is a fungal infection)
  2. Cheilitis (infection of lips)
  3. Pyrexia (fever)
  4. Rhinorrhoea (watery mucus discharge from the nose)
  5. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  6. Throat tightness
  7. Kidney infection
  8. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  9. Asthenia (weakness)
  10. Eye haemorrhage (bleeding in the eye)

What are the existing conditions these people have? *

  1. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 11 people, 35.48%
  2. Constipation: 7 people, 22.58%
  3. Cat Scratch Disease (bacterial infection by cat scratch): 6 people, 19.35%
  4. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 6 people, 19.35%
  5. Borrelia Infection (infectious disease caused by bacteria belonging to the genus borrelia): 5 people, 16.13%
  6. Babesiosis (malaria-like parasitic disease caused by infection with babesia): 4 people, 12.90%
  7. Postural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright): 4 people, 12.90%
  8. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 4 people, 12.90%
  9. Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 4 people, 12.90%
  10. Indigestion: 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gleevec and Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gleevec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gleevec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on imatinib mesylate and azithromycin (the active ingredients of Gleevec and Azithromycin, respectively), and Gleevec and Azithromycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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