Gleevec and Clarinex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Clarinex (desloratadine). Common drug interactions include rash among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Gleevec and Clarinex. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Clarinex?

Clarinex has active ingredients of desloratadine. It is often used in allergies. eHealthMe is studying from 6,463 Clarinex users. Check the latest studies of Clarinex.

On Jul, 28, 2026

13 people who take Gleevec and Clarinex together, and have interactions are studied.

What are the common drug interactions of Gleevec and Clarinex, by gender? *:

female:

Rash
Antinuclear antibody positive
Pyrexia (fever)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Weight increased
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Diarrhoea
Faeces discoloured
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hepatic enzyme increased

male:

Pruritus (severe itching of the skin)
Rash
Immunosuppression
Intracranial tumour haemorrhage (bleeding tumour in brain)
Malignant neoplasm progression (cancer tumour came back)
Pneumonia
Staphylococcal infection (an infection with staphylococcus bacteria)
Vascular bypass dysfunction
Skin disorder (skin disease)
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Gleevec and Clarinex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Delayed recovery from anaesthesia
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Vascular bypass dysfunction

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abasia (inability to walk)
Back pain
Intervertebral disc protrusion (spinal disc protrusion)
Intervertebral disc space narrowing (spinal disc space narrowing)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Periorbital oedema (swelling around the eyes)
Vomiting
Death

60+:

Rash
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Splenic lesion (lesion on spleen)
Upper respiratory tract infection
Wheezing (a high-pitched whistling sound made while you breath)
Antinuclear antibody positive
Pyrexia (fever)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Weight increased
Eye swelling

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 23.08%
Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 15.38%
Gastrointestinal Stromal Tumor: 2 people, 15.38%
Tumor: 1 person, 7.69%
Rectosigmoid Cancer (cancer that originates in the rectum and sigmoid colon): 1 person, 7.69%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 7.69%
Pain: 1 person, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 7.69%
Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 1 person, 7.69%
Asplenia (absence of normal spleen function and is associated with some serious infection risks): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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