Gleevec and Gentamicin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Gentamicin (gentamicin sulfate). Common drug interactions include tinnitus among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Gleevec and Gentamicin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Gleevec?
Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.
What is Gentamicin?
Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.
19 people who take Gleevec and Gentamicin together, and have interactions are studied.

What are the common drug interactions of Gleevec and Gentamicin, by gender? *:
female:
- Tinnitus (a ringing in the ears)
- Upper respiratory tract infection
- Wheezing (a high-pitched whistling sound made while you breath)
- Aplasia (defective development or congenital absence of an organ or tissue)
- Blood albumin decreased
- Blood bilirubin increased
- Chest discomfort
- Coma (state of unconsciousness lasting more than six hours)
- Dyspnoea (difficult or laboured respiration)
- Infusion site pruritus (severe itching at infusion site)
male:
- Anaemia (lack of blood)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Aphagia (inability or refusal to swallow)
- Corneal oedema (corneal swelling)
- Dacryocanaliculitis (1. inflammation of the lacrimal ducts. 2. inflammation of the lacrimal sac and lacrimal canaliculi)
- Dehydration (dryness resulting from the removal of water)
- Drug resistance (reduction in effectiveness of a drug)
- Eye abscess
- Eye pruritus (eye itching)
- Fluid retention (an abnormal accumulation of fluid in the blood)
What are the common drug interactions of Gleevec and Gentamicin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Aplasia (defective development or congenital absence of an organ or tissue)
- Lung infection
- Mucosal inflammation (infection of mucous membrane)
- Respiratory distress (difficulty in breathing)
- Septic shock (shock due to blood infection)
- Streptococcal sepsis (whole body inflammation by streptococcal)
30-39:
n/a
40-49:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Aphagia (inability or refusal to swallow)
- Corneal oedema (corneal swelling)
- Dacryocanaliculitis (1. inflammation of the lacrimal ducts. 2. inflammation of the lacrimal sac and lacrimal canaliculi)
- Dehydration (dryness resulting from the removal of water)
- Drug resistance (reduction in effectiveness of a drug)
- Eye abscess
- Eye pruritus (eye itching)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Generalised oedema (swelling all over the body)
50-59:
n/a
60+:
- Neutropenia (an abnormally low number of neutrophils)
- Anaemia (lack of blood)
- Coma (state of unconsciousness lasting more than six hours)
- Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
- Lactic acidosis (low ph in body tissues)
- Lung disorder (lung disease)
- Nosocomial infection (infection from hospital)
- Pleural effusion (water on the lungs)
- Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
- Quadriplegia (a four limb paralysis)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 5 people, 26.32%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 26.32%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 10.53%
- Neoplasm Recurrence (reoccurrence of tumour): 1 person, 5.26%
- Keratitis Fungal (inflammation of the cornea due to fungal organism): 1 person, 5.26%
- Fever: 1 person, 5.26%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1 person, 5.26%
- Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 1 person, 5.26%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Gleevec and Gentamicin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Gleevec (35,415 reports)
- Gentamicin (21,654 reports)
Browse all drug interactions of Gleevec and Gentamicin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gleevec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gentamicin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gleevec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gentamicin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on imatinib mesylate and gentamicin sulfate (the active ingredients of Gleevec and Gentamicin, respectively), and Gleevec and Gentamicin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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