Gleevec and Valsartan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Valsartan (valsartan). Common drug interactions include malaise among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Gleevec and Valsartan. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Valsartan?

Valsartan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 63,805 Valsartan users. Check the latest studies of Valsartan.



On Jul, 11, 2026

40 people who take Gleevec and Valsartan together, and have interactions are studied.

Gleevec and Valsartan drug interactions.

What are the common drug interactions of Gleevec and Valsartan, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Muscle spasms (muscle contraction)
  3. Nausea (feeling of having an urge to vomit)
  4. Abdominal pain upper
  5. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  6. Acute psychosis (period of mentally unstable behaviour)
  7. Alopecia (absence of hair from areas of the body)
  8. Anaemia (lack of blood)
  9. Arthropathy
  10. Asthenia (weakness)

male:

  1. Fatigue (feeling of tiredness)
  2. Hypotension (abnormally low blood pressure)
  3. Neuropathy peripheral (surface nerve damage)
  4. Restlessness (not able to rest)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Weight decreased
  8. Abdominal discomfort
  9. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  10. Haematochezia (passage of stools containing blood)

What are the common drug interactions of Gleevec and Valsartan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Acute psychosis (period of mentally unstable behaviour)
  2. Drug ineffective
  3. Dry mouth
  4. Galactorrhoea (secretion of breast milk in men)
  5. Muscle spasms (muscle contraction)
  6. Periorbital oedema (swelling around the eyes)
  7. Rash
  8. Swelling

40-49:

  1. Pancreatitis (inflammation of pancreas)
  2. Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
  3. Platelet count decreased
  4. Pleural effusion (water on the lungs)
  5. Purulence (containing pus)
  6. Renal failure acute (rapid kidney dysfunction)
  7. Small intestinal obstruction (blockage in small intestine)
  8. Soft tissue necrosis (death of soft tissue)
  9. Transaminases increased
  10. Viral infection

50-59:

  1. Optic neuritis (optic nerve inflammation)
  2. Pancreatitis acute (sudden inflammation of pancreas)

60+:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Joint swelling
  4. Oedema peripheral (superficial swelling)
  5. Periorbital oedema (swelling around the eyes)
  6. Weight decreased
  7. Dizziness
  8. Abdominal discomfort
  9. Abdominal pain
  10. Abdominal pain upper

What are the existing conditions these people have? *

  1. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 14 people, 35.00%
  2. Gastrointestinal Stromal Tumor: 6 people, 15.00%
  3. Stress And Anxiety: 4 people, 10.00%
  4. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 7.50%
  5. Pain: 2 people, 5.00%
  6. High Blood Cholesterol: 2 people, 5.00%
  7. Diabetes: 2 people, 5.00%
  8. Depression: 2 people, 5.00%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 5.00%
  10. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gleevec and Valsartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gleevec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valsartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gleevec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valsartan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on imatinib mesylate and valsartan (the active ingredients of Gleevec and Valsartan, respectively), and Gleevec and Valsartan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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