Gliclazide and Aprepitant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gliclazide (gliclazide) and Aprepitant (aprepitant). Common drug interactions include hyponatraemia among females and anaphylactic reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Gliclazide and Aprepitant. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Gliclazide?

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.



On Jul, 09, 2026

28 people who take Gliclazide and Aprepitant together, and have interactions are studied.

Gliclazide and Aprepitant drug interactions.

What are the common drug interactions of Gliclazide and Aprepitant, by gender? *:

female:

  1. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  2. Nausea (feeling of having an urge to vomit)
  3. Vomiting
  4. Pneumonia
  5. Arthralgia (joint pain)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Abdominal pain lower
  8. Alopecia (absence of hair from areas of the body)
  9. Back pain
  10. Chest pain

male:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Cardiac arrest
  3. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  4. Chills (felling of cold)
  5. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
  6. Mesothelioma malignant (cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium)
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Urinary tract infection
  9. Vomiting
  10. Asthenia (weakness)

What are the common drug interactions of Gliclazide and Aprepitant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hypertension (high blood pressure)

50-59:

n/a

60+:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Cellulitis (infection under the skin)
  6. Pneumonia
  7. Renal failure (kidney dysfunction)
  8. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  9. Arthralgia (joint pain)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

  1. High Blood Pressure: 7 people, 25.00%
  2. Diarrhea: 6 people, 21.43%
  3. Breast Cancer: 5 people, 17.86%
  4. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 4 people, 14.29%
  5. Nausea And Vomiting: 4 people, 14.29%
  6. Cervix Carcinoma (cancer of cervix): 3 people, 10.71%
  7. Cervix Carcinoma Recurrent (repeated cancer of cervix): 3 people, 10.71%
  8. Stomatitis (inflammation of mucous membrane of mouth): 3 people, 10.71%
  9. Dyslipidaemia (abnormal amount of lipids): 3 people, 10.71%
  10. Enteritis (inflammation of the small intestine): 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

Do you take Gliclazide and Aprepitant?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gliclazide and Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gliclazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gliclazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aprepitant and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gliclazide and aprepitant (the active ingredients of Gliclazide and Aprepitant, respectively), and Gliclazide and Aprepitant (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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