Gliclazide and Co-codamol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gliclazide (gliclazide) and Co-codamol (acetaminophen; codeine phosphate). Common drug interactions include pulmonary oedema among females and jaundice among males.
The phase IV clinical study analyzes what interactions people have when they take Gliclazide and Co-codamol. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.
What is Gliclazide?
Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.
What is Co-codamol?
Co-codamol has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 2,364 Co-codamol users. Check the latest studies of Co-codamol.
64 people who take Gliclazide and Co-codamol together, and have interactions are studied.

What are the common drug interactions of Gliclazide and Co-Codamol, by gender? *:
female:
- Pulmonary oedema (fluid accumulation in the lungs)
- Swelling
- Swelling face
- Weight increased
- Wheezing (a high-pitched whistling sound made while you breath)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac failure
- Vomiting
- Fall
- Headache (pain in head)
male:
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Nausea (feeling of having an urge to vomit)
- Renal impairment (severely reduced kidney function)
- Vomiting
- Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
- Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
What are the common drug interactions of Gliclazide and Co-Codamol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Syncope (loss of consciousness with an inability to maintain postural tone)
50-59:
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
- Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Cough
- Diabetic microangiopathy (small blood vessels of the body are damaged due to diabetes)
- Dizziness
- Dyslipidaemia (abnormal amount of lipids)
- Hypertension (high blood pressure)
- Lower respiratory tract infection
60+:
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Glomerular filtration rate decreased
- Diabetes mellitus inadequate control
- Lower respiratory tract infection
- Pulmonary oedema (fluid accumulation in the lungs)
- Vomiting
- Dyspnoea (difficult or laboured respiration)
- Fall
- Headache (pain in head)
- Hypersensitivity
What are the existing conditions these people have? *
- Type 2 Diabetes: 20 people, 31.25%
- High Blood Cholesterol: 13 people, 20.31%
- High Blood Pressure: 7 people, 10.94%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 7.81%
- Gastric Disorder (disease of stomach): 4 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Gliclazide and Co-codamol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Gliclazide (28,131 reports)
- Co-codamol (2,364 reports)
Browse all drug interactions of Gliclazide and Co-codamol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gliclazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Co-codamol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gliclazide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Co-codamol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on gliclazide and acetaminophen; codeine phosphate (the active ingredients of Gliclazide and Co-codamol, respectively), and Gliclazide and Co-codamol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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