Gliclazide and Nadolol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gliclazide (gliclazide) and Nadolol (nadolol). Common drug interactions include atypical femur fracture among females and bacteraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Gliclazide and Nadolol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Gliclazide?

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.

What is Nadolol?

Nadolol has active ingredients of nadolol. It is often used in high blood pressure. eHealthMe is studying from 4,476 Nadolol users. Check the latest studies of Nadolol.



On Jul, 08, 2026

13 people who take Gliclazide and Nadolol together, and have interactions are studied.

Gliclazide and Nadolol drug interactions.

What are the common drug interactions of Gliclazide and Nadolol, by gender? *:

female:

  1. Atypical femur fracture
  2. Humerus fracture (injury to the upper arm bone)
  3. Arthralgia (joint pain)
  4. Back pain
  5. Cellulitis (infection under the skin)
  6. Death
  7. Dysuria (painful or difficult urination)
  8. Escherichia sepsis (bacterial infection by escherichia coli)
  9. Heart rate decreased
  10. Hypotension (abnormally low blood pressure)

male:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Atrioventricular block (heart block)
  4. Headache (pain in head)
  5. Hypersensitivity
  6. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
  7. Chorioretinitis (an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye)
  8. Hepatotoxicity (chemical-driven liver damage)
  9. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  10. Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)

What are the common drug interactions of Gliclazide and Nadolol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
  4. Chorioretinitis (an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye)
  5. Hepatotoxicity (chemical-driven liver damage)
  6. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  7. Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
  8. Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)
  9. Systemic candida (whole body fungal infection)
  10. Atypical femur fracture

60+:

  1. Loss of consciousness
  2. Arthralgia (joint pain)
  3. Weight increased
  4. Atrioventricular block (heart block)
  5. Back pain
  6. Dysuria (painful or difficult urination)
  7. Escherichia sepsis (bacterial infection by escherichia coli)
  8. Headache (pain in head)
  9. Hypersensitivity
  10. Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 38.46%
  2. Osteoporosis (bones weak and more likely to break): 3 people, 23.08%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  4. Quit Smoking: 1 person, 7.69%
  5. Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 7.69%
  6. Psoriasis (immune-mediated disease that affects the skin): 1 person, 7.69%
  7. Interstitial Lung Disease: 1 person, 7.69%
  8. Gout (uric acid crystals building up in the body): 1 person, 7.69%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.69%
  10. Cardiac Failure Congestive: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gliclazide and Nadolol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gliclazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nadolol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gliclazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nadolol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gliclazide and nadolol (the active ingredients of Gliclazide and Nadolol, respectively), and Gliclazide and Nadolol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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