Gliclazide and Rapamune drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gliclazide (gliclazide) and Rapamune (sirolimus). Common drug interactions include acne among females and cholecystitis acute among males.
The phase IV clinical study analyzes what interactions people have when they take Gliclazide and Rapamune. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.
What is Gliclazide?
Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.
What is Rapamune?
Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.
71 people who take Gliclazide and Rapamune together, and have interactions are studied.

What are the common drug interactions of Gliclazide and Rapamune, by gender? *:
female:
- Acne (skin problems that cause pimples)
- Alopecia (absence of hair from areas of the body)
- Ovarian cyst (fluid filled sac of the ovary)
- Transplant rejection (a transplant material is not worked)
- Pain
- Pneumonia
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
- Overdose
- Drug ineffective
male:
- Cholecystitis acute (rapid infection of gallbladder)
- Renal failure acute (rapid kidney dysfunction)
- Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gastroenteritis helicobacter (inflammation of stomach and intestine caused by helicobacter infection)
- Glomerular filtration rate decreased
- Immunosuppressant drug level increased
- Kidney transplant rejection
- Metastases to liver (cancer spreads to liver)
- Nausea (feeling of having an urge to vomit)
- Nephropathy toxic (damage to kidney due to toxins)
What are the common drug interactions of Gliclazide and Rapamune, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Acne (skin problems that cause pimples)
- Alopecia (absence of hair from areas of the body)
- Ovarian cyst (fluid filled sac of the ovary)
- Transplant rejection (a transplant material is not worked)
- Pain
- Pneumonia
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
- Overdose
- Drug ineffective
50-59:
- Cholecystitis acute (rapid infection of gallbladder)
60+:
- Renal failure acute (rapid kidney dysfunction)
- Drug level increased
- Blood creatinine increased
- Blood potassium increased
- Blood urea increased
- Glomerular filtration rate decreased
- Immunosuppressant drug level increased
- Kidney transplant rejection
- Nephropathy toxic (damage to kidney due to toxins)
- Proteinuria (presence of protein in the urine)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 46 people, 64.79%
- Transplant Rejection (a transplant material is not worked): 9 people, 12.68%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 4 people, 5.63%
- Muscle Aches (muscle pain): 4 people, 5.63%
* Approximation only. Some reports may have incomplete information.
Do you take Gliclazide and Rapamune?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Gliclazide (28,131 reports)
- Rapamune (13,848 reports)
Browse all drug interactions of Gliclazide and Rapamune:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gliclazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rapamune:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gliclazide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rapamune and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on gliclazide and sirolimus (the active ingredients of Gliclazide and Rapamune, respectively), and Gliclazide and Rapamune (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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