Glipizide and Estropipate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glipizide (glipizide) and Estropipate (estropipate). Common drug interactions include asthenia among females.

The phase IV clinical study analyzes what interactions people have when they take Glipizide and Estropipate. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

What is Estropipate?

Estropipate has active ingredients of estropipate. It is often used in hormone replacement therapy. eHealthMe is studying from 1,659 Estropipate users. Check the latest studies of Estropipate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

20 people who take Glipizide and Estropipate together, and have interactions are studied.

Glipizide and Estropipate drug interactions.

What are the common drug interactions of Glipizide and Estropipate, by gender? *:

female:

Asthenia (weakness)
Injury
Neck pain
Peripheral swelling
Spinal pain (pain in spine)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Blood glucose increased
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression

male:

n/a

What are the common drug interactions of Glipizide and Estropipate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Breast cancer female

60+:

Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Asthenia (weakness)
Abdominal discomfort
Acute myocardial infarction (acute heart attack)
Alanine aminotransferase increased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Aspartate aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Back pain
Blood amylase increased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 45.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 40.00%
High Blood Cholesterol: 2 people, 10.00%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 5.00%
Pain: 1 person, 5.00%
Osteoporosis (bones weak and more likely to break): 1 person, 5.00%
Oedema (fluid collection in tissue): 1 person, 5.00%
Low Density Lipoprotein Increased (cholesterol increased in blood): 1 person, 5.00%
Insomnia (sleeplessness): 1 person, 5.00%
Hypokalemia (low potassium): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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