Glipizide and Medroxyprogesterone acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glipizide (glipizide) and Medroxyprogesterone acetate (medroxyprogesterone acetate). Common drug interactions include constipation among females and transient ischaemic attack among males.

The phase IV clinical study analyzes what interactions people have when they take Glipizide and Medroxyprogesterone acetate. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

What is Medroxyprogesterone acetate?

Medroxyprogesterone acetate has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 12,600 Medroxyprogesterone acetate users. Check the latest studies of Medroxyprogesterone acetate.



On Jul, 08, 2026

27 people who take Glipizide and Medroxyprogesterone acetate together, and have interactions are studied.

Glipizide and Medroxyprogesterone acetate drug interactions.

What are the common drug interactions of Glipizide and Medroxyprogesterone Acetate, by gender? *:

female:

  1. Constipation
  2. Chest pain
  3. Dyspnoea (difficult or laboured respiration)
  4. Foot deformity (functional disability of foot)
  5. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  6. Dizziness
  7. Chronic kidney disease
  8. Fatigue (feeling of tiredness)
  9. Nephrogenic anaemia (anaemia due to kidney disease)
  10. Renal failure (kidney dysfunction)

male:

  1. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the common drug interactions of Glipizide and Medroxyprogesterone Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug hypersensitivity
  2. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  3. Suicidal behaviour

30-39:

  1. Back pain
  2. Difficulty in micturition (difficulty to urinate)
  3. Pyrexia (fever)
  4. Tenderness (pain or discomfort when an affected area is touched)
  5. Weakness

40-49:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  6. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

50-59:

  1. Constipation
  2. Dislocation of vertebra
  3. Abdominal discomfort
  4. Headache (pain in head)
  5. Nausea (feeling of having an urge to vomit)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Chest pain
  9. Dyspnoea (difficult or laboured respiration)
  10. Foot deformity (functional disability of foot)

60+:

  1. Breast cancer female
  2. Renal failure acute (rapid kidney dysfunction)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Impaired driving ability
  5. Nerve injury
  6. Vision blurred
  7. Wound
  8. Alopecia (absence of hair from areas of the body)
  9. Oedema lower limb (fluid collection in tissue of lower leg)
  10. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the existing conditions these people have? *

  1. Hyperkalemia (damage to or disease of the kidney): 10 people, 37.04%
  2. High Blood Pressure: 3 people, 11.11%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 11.11%
  4. Migraine (headache): 3 people, 11.11%
  5. Urinary Tract Infection: 2 people, 7.41%
  6. Cluster Headache (one-sided head pain with tearing): 2 people, 7.41%
  7. Fever: 2 people, 7.41%
  8. Endometrial Hyperplasia (enlargement of uterus wall): 2 people, 7.41%
  9. Dizziness: 2 people, 7.41%
  10. Depression: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glipizide and Medroxyprogesterone acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glipizide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Medroxyprogesterone acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glipizide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Medroxyprogesterone acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glipizide and medroxyprogesterone acetate (the active ingredients of Glipizide and Medroxyprogesterone acetate, respectively), and Glipizide and Medroxyprogesterone acetate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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