Glipizide and Neoral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glipizide (glipizide) and Neoral (cyclosporine). Common drug interactions include dyspnoea among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Glipizide and Neoral. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

What is Neoral?

Neoral has active ingredients of cyclosporine. It is often used in psoriasis. eHealthMe is studying from 26,084 Neoral users. Check the latest studies of Neoral.



On Jul, 07, 2026

37 people who take Glipizide and Neoral together, and have interactions are studied.

Glipizide and Neoral drug interactions.

What are the common drug interactions of Glipizide and Neoral, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Headache (pain in head)
  3. Hyperkalaemia (damage to or disease of the kidney)
  4. Hypertension (high blood pressure)
  5. Hypotension (abnormally low blood pressure)
  6. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  7. Renal tubular necrosis (death of kidney tubules)
  8. Urine analysis abnormal
  9. Vomiting
  10. Arrhythmia (irregular heartbeat)

male:

  1. Asthenia (weakness)
  2. Nausea (feeling of having an urge to vomit)
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Gynaecomastia (enlargement of the gland tissue of the male breast)
  5. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  6. Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
  7. Pleural effusion (water on the lungs)
  8. Pruritus (severe itching of the skin)
  9. Scab (a hard coating on the skin formed during the wound healing)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Glipizide and Neoral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Aspergilloma (fungus ball, is a clump of fungus which exists in a body cavity such as the lung)
  2. Biliary tract disorder
  3. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  4. Drug toxicity
  5. Encephalitis (inflammation of the brain)
  6. Fungal infection
  7. Headache (pain in head)
  8. Infection
  9. Lymphoma (cancer that begins in immune system cells)
  10. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)

30-39:

n/a

40-49:

  1. Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
  2. Blood bicarbonate decreased
  3. Blood creatinine increased
  4. Blood osmolarity increased
  5. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  6. Diarrhoea
  7. Hyperkalaemia (damage to or disease of the kidney)
  8. Hypotension (abnormally low blood pressure)
  9. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  10. Urine analysis abnormal

50-59:

  1. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Platelet count decreased
  4. Pruritus (severe itching of the skin)
  5. Pyrexia (fever)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Seroma (a tumour like collection of serum in the tissues)
  8. Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
  9. Post procedural complication
  10. Renal tubular necrosis (death of kidney tubules)

60+:

  1. Asthenia (weakness)
  2. Nausea (feeling of having an urge to vomit)
  3. Drug ineffective
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  7. Chronic kidney disease
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Diarrhoea
  10. Graft rejection (graft failure)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.81%
  2. High Blood Pressure: 3 people, 8.11%
  3. High Blood Cholesterol: 3 people, 8.11%
  4. Depression: 3 people, 8.11%
  5. Multiple Myeloma (cancer of the plasma cells): 2 people, 5.41%
  6. Multiple Allergies (allergy to multiple agents): 2 people, 5.41%
  7. Insomnia (sleeplessness): 2 people, 5.41%
  8. Immunodeficiency Disorders: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glipizide and Neoral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glipizide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Neoral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glipizide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Neoral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glipizide and cyclosporine (the active ingredients of Glipizide and Neoral, respectively), and Glipizide and Neoral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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