Glipizide and Protamine sulfate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glipizide (glipizide) and Protamine sulfate (protamine sulfate). Common drug interactions include myocardial infarction among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Glipizide and Protamine sulfate. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.
What is Glipizide?
Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.
What is Protamine sulfate?
Protamine sulfate has active ingredients of protamine sulfate. eHealthMe is studying from 3,292 Protamine sulfate users. Check the latest studies of Protamine sulfate.
68 people who take Glipizide and Protamine sulfate together, and have interactions are studied.

What are the common drug interactions of Glipizide and Protamine Sulfate, by gender? *:
female:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
- Renal disorder (kidney disease)
- Swelling face
- Atrioventricular block complete (heart block complete)
- Bradycardia (abnormally slow heart action)
- Cardiac arrest
- Hypotension (abnormally low blood pressure)
- Petit mal epilepsy (absence seizure)
- Psychiatric symptom
male:
- Pain
- Renal failure (kidney dysfunction)
- Multi-organ failure (multisystem organ failure)
- Death
- Depression
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Nervousness
- Blindness unilateral
- Psychological trauma
- Renal disorder (kidney disease)
What are the common drug interactions of Glipizide and Protamine Sulfate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anxiety
- Fear
- Injury
- Pain
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Depression
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Emotional distress
- Multi-organ failure (multisystem organ failure)
50-59:
- Pyrexia (fever)
- Renal failure acute (rapid kidney dysfunction)
- Renal failure chronic (long lasting kidney dysfunction)
- Rhinorrhoea (watery mucus discharge from the nose)
- Scar
- Sinusitis (inflammation of sinus)
- Skin ulcer
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tardive dyskinesia (a disorder that involves involuntary movements)
60+:
- Renal failure (kidney dysfunction)
- Pain
- Death
- Multi-organ failure (multisystem organ failure)
- Depression
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Renal disorder (kidney disease)
- Blindness unilateral
- Nervousness
- Asthenia (weakness)
What are the existing conditions these people have? *
- High Blood Pressure: 4 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Glipizide and Protamine sulfate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Glipizide (64,852 reports)
- Protamine sulfate (3,292 reports)
Browse all drug interactions of Glipizide and Protamine sulfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glipizide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Protamine sulfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glipizide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protamine sulfate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on glipizide and protamine sulfate (the active ingredients of Glipizide and Protamine sulfate, respectively), and Glipizide and Protamine sulfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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