Glipizide and Repaglinide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glipizide (glipizide) and Repaglinide (repaglinide). Common drug interactions include nausea among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Glipizide and Repaglinide. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.
What is Glipizide?
Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.
What is Repaglinide?
Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.
81 people who take Glipizide and Repaglinide together, and have interactions are studied.

What are the common drug interactions of Glipizide and Repaglinide, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Weight decreased
- Photopsia (presence of perceived flashes of light)
- Abdominal distension
- Abdominal pain upper
- Activities of daily living impaired
- Anaemia (lack of blood)
- Anxiety
male:
- Chronic kidney disease
- Constipation
- Coma (state of unconsciousness lasting more than six hours)
- Hypertension (high blood pressure)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood)
- Cardiac failure
- Depression
- Anaemia postoperative
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
What are the common drug interactions of Glipizide and Repaglinide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Diabetes mellitus inadequate control
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Memory impairment
- Tremor (trembling or shaking movements in one or more parts of your body)
- Activities of daily living impaired
- Ageusia (loss of taste functions of the tongue)
- Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
- Blood glucose decreased
- Blood glucose increased
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Burning sensation
- Cardiomegaly (increased size of heart than normal)
60+:
- Constipation
- Chronic kidney disease
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Coma (state of unconsciousness lasting more than six hours)
- Hypertension (high blood pressure)
- Hypoaesthesia (reduced sense of touch or sensation)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Nausea (feeling of having an urge to vomit)
- Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood)
- Cardiac failure
What are the existing conditions these people have? *
- Type 2 Diabetes: 18 people, 22.22%
- High Blood Pressure: 13 people, 16.05%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 13.58%
- High Blood Cholesterol: 8 people, 9.88%
- Cardiac Disorder: 7 people, 8.64%
- Pain: 5 people, 6.17%
* Approximation only. Some reports may have incomplete information.
Do you take Glipizide and Repaglinide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Glipizide (64,852 reports)
- Repaglinide (8,226 reports)
Browse all drug interactions of Glipizide and Repaglinide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glipizide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Repaglinide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glipizide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Repaglinide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on glipizide and repaglinide (the active ingredients of Glipizide and Repaglinide, respectively), and Glipizide and Repaglinide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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