Glivec and Ambisome drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glivec (imatinib mesylate) and Ambisome (amphotericin b). Common drug interactions include malaise among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Glivec and Ambisome. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Glivec?

Glivec has active ingredients of imatinib mesylate. eHealthMe is studying from 17,777 Glivec users. Check the latest studies of Glivec.

What is Ambisome?

Ambisome has active ingredients of amphotericin b. eHealthMe is studying from 7,934 Ambisome users. Check the latest studies of Ambisome.



On Jul, 20, 2026

15 people who take Glivec and Ambisome together, and have interactions are studied.

Glivec and Ambisome drug interactions.

What are the common drug interactions of Glivec and Ambisome, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Pyrexia (fever)
  3. Cryptococcosis (potentially fatal fungal disease)
  4. Dementia (madness)
  5. Folliculitis (infection of hair root)
  6. Herpes zoster
  7. Hypofibrinogenaemia (a decrease in plasma fibrogen level)
  8. Hypokalaemia (low potassium)
  9. Liver disorder (liver diseases)
  10. Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)

male:

  1. Drug hypersensitivity
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Rotavirus infection
  4. Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
  5. Stomatitis (inflammation of mucous membrane of mouth)
  6. Upper respiratory tract infection
  7. Conjunctivitis (pink eye)
  8. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  9. Device related infection
  10. Constipation

What are the common drug interactions of Glivec and Ambisome, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Drug hypersensitivity
  2. Abdominal pain
  3. Anal inflammation
  4. Catheter site infection (infection at the site of insertion)
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Gastrointestinal viral infection (virus infection of gastrointestinal tract)
  7. Hypokalaemia (low potassium)
  8. Nausea (feeling of having an urge to vomit)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Pyrexia (fever)

10-19:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Alanine aminotransferase increased
  3. Anaemia (lack of blood)
  4. Arthralgia (joint pain)
  5. Aspartate aminotransferase increased
  6. Cardiac failure
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Hypoxia (low oxygen in tissues)
  9. Leukocytosis (increased white blood cells)
  10. Neutropenia (an abnormally low number of neutrophils)

20-29:

n/a

30-39:

n/a

40-49:

  1. Renal failure (kidney dysfunction)

50-59:

  1. Cryptococcosis (potentially fatal fungal disease)
  2. Dementia (madness)
  3. Folliculitis (infection of hair root)
  4. Herpes zoster
  5. Hypofibrinogenaemia (a decrease in plasma fibrogen level)
  6. Hypokalaemia (low potassium)
  7. Liver disorder (liver diseases)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
  10. Oedema (fluid collection in tissue)

60+:

  1. Acute respiratory failure
  2. Blood creatine phosphokinase increased
  3. White blood cell count increased
  4. Drug ineffective
  5. Chills (felling of cold)
  6. Circulatory collapse
  7. Diarrhoea
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 11 people, 73.33%
  2. Leukaemia (blood or bone marrow cancer): 9 people, 60.00%
  3. High Blood Pressure: 2 people, 13.33%
  4. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 13.33%
  5. Joint Pain: 1 person, 6.67%
  6. Insomnia (sleeplessness): 1 person, 6.67%
  7. Febrile Neutropenia (fever with reduced white blood cells): 1 person, 6.67%
  8. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 1 person, 6.67%
  9. Depression: 1 person, 6.67%
  10. Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Glivec and Ambisome?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glivec and Ambisome:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glivec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ambisome:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glivec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambisome and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on imatinib mesylate and amphotericin b (the active ingredients of Glivec and Ambisome, respectively), and Glivec and Ambisome (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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