Glucosamine and Boniva drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glucosamine (glucosamine) and Boniva (ibandronate sodium). Common drug interactions include vertebral foraminal stenosis among females and constipation among males.
The phase IV clinical study analyzes what interactions people have when they take Glucosamine and Boniva. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.
What is Glucosamine?
Glucosamine has active ingredients of glucosamine. It is often used in joint pain. eHealthMe is studying from 15,547 Glucosamine users. Check the latest studies of Glucosamine.
What is Boniva?
Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.
55 people who take Glucosamine and Boniva together, and have interactions are studied.

What are the common drug interactions of Glucosamine and Boniva, by gender? *:
female:
- Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
- Impaired healing
- Foot fracture
- Pain in extremity
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Fracture nonunion (permanent failure of healing following a broken bone)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Acetabulum fracture (socket of the hip joint- fracture)
- Acquired claw toe (acquired musculoskeletal deformities)
- Adverse event
male:
- Constipation
- Gait disturbance
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cellulitis (infection under the skin)
- Chest discomfort
- Cough
- Crystal arthropathy (accumulation of crystals in joints)
- Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
- Depression
- Diarrhoea
What are the common drug interactions of Glucosamine and Boniva, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Blood pressure increased
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Coma (state of unconsciousness lasting more than six hours)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Gait disturbance
- Gallbladder disorder
- Haemorrhage (bleeding)
- Liver disorder (liver diseases)
- Local swelling (swelling at the site of some application of substance or injury)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Neck pain
- Pain in extremity
- Sinus disorder (disease of sinus)
- Skin burning sensation
- Tooth extraction
- Tooth infection
- Injection site pain
- Myalgia (muscle pain)
- Calcinosis (calcium deposits in any soft tissue)
- Dizziness
60+:
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Femur fracture
- Insomnia (sleeplessness)
- Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
- Back pain
- Bone marrow oedema syndrome (transient clinical conditions -the disease mainly affects the hip, the knee, and the ankle of middle-aged males)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Joint dislocation (a joint position is changed from normal position)
- Muscle spasms (muscle contraction)
- Pathological fracture (broken bone caused by disease)
What are the existing conditions these people have? *
- Osteopenia (a condition where bone mineral density is lower than normal): 13 people, 23.64%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 14.55%
- High Blood Pressure: 5 people, 9.09%
- Renal Cell Carcinoma (a kidney cancer): 3 people, 5.45%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 5.45%
- Depression: 3 people, 5.45%
* Approximation only. Some reports may have incomplete information.
Do you take Glucosamine and Boniva?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Glucosamine (15,547 reports)
- Boniva (27,340 reports)
Browse all drug interactions of Glucosamine and Boniva:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glucosamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Boniva:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glucosamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Boniva and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on glucosamine and ibandronate sodium (the active ingredients of Glucosamine and Boniva, respectively), and Glucosamine and Boniva (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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