Glucosamine and Opdivo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glucosamine (glucosamine) and Opdivo (nivolumab). Common drug interactions include cough among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Glucosamine and Opdivo. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Glucosamine?

Glucosamine has active ingredients of glucosamine. It is often used in joint pain. eHealthMe is studying from 15,547 Glucosamine users. Check the latest studies of Glucosamine.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.



On Jul, 15, 2026

38 people who take Glucosamine and Opdivo together, and have interactions are studied.

Glucosamine and Opdivo drug interactions.

What are the common drug interactions of Glucosamine and Opdivo, by gender? *:

female:

  1. Cough
  2. Death
  3. Joint stiffness
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Peripheral swelling
  6. Rash generalised (rash on most of body parts)
  7. Axonal neuropathy (dysfunction of axon nerves)
  8. Blood pressure fluctuation
  9. Diarrhoea
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

male:

  1. Fatigue (feeling of tiredness)
  2. Diarrhoea
  3. Death
  4. Pain in extremity
  5. Constipation
  6. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Renal cell carcinoma recurrent (reoccurrence of kidney cancer)
  9. Pruritus (severe itching of the skin)
  10. Blood creatinine increased

What are the common drug interactions of Glucosamine and Opdivo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Adverse event

60+:

  1. Fatigue (feeling of tiredness)
  2. Diarrhoea
  3. Death
  4. Pain in extremity
  5. Constipation
  6. Cough
  7. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  8. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  9. Renal cell carcinoma recurrent (reoccurrence of kidney cancer)
  10. Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 11 people, 28.95%
  2. Multiple Myeloma (cancer of the plasma cells): 6 people, 15.79%
  3. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 7.89%
  4. Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 7.89%
  5. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 3 people, 7.89%
  6. High Blood Pressure: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Glucosamine and Opdivo?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glucosamine and Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glucosamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glucosamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Opdivo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on glucosamine and nivolumab (the active ingredients of Glucosamine and Opdivo, respectively), and Glucosamine and Opdivo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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