Glucotrol and Alphagan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glucotrol (glipizide) and Alphagan (brimonidine tartrate). Common drug interactions include diabetic neuropathy among females and drug dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Glucotrol and Alphagan. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Glucotrol?

Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

On Aug, 02, 2026

85 people who take Glucotrol and Alphagan together, and have interactions are studied.

Glucotrol and Alphagan drug interactions.

What are the common drug interactions of Glucotrol and Alphagan, by gender? *:

female:

Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Pancreatitis chronic (chronic inflammation of pancreas)
Weight increased
Blood pressure fluctuation
Chest pain
Dyspnoea (difficult or laboured respiration)
Fall
Polyp colorectal
Rib fracture
Suicidal behaviour

male:

Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Insomnia (sleeplessness)
Pain
Pyrexia (fever)
Syncope (loss of consciousness with an inability to maintain postural tone)
Weight decreased
Abdominal pain
Alanine aminotransferase increased
Arthralgia (joint pain)

What are the common drug interactions of Glucotrol and Alphagan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abdominal pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular disorder (disease of brain)
Chest pain
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrointestinal pain
Hypertension (high blood pressure)
Non-cardiac chest pain

50-59:

Weight decreased
Anger
Blood pressure increased
Confusional state
Drug ineffective
Dyspepsia (indigestion)
Heart rate increased
Injection site haemorrhage (bleeding from injection site)
Nervousness
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

60+:

Fall
Pain
Cough
Muscle spasms (muscle contraction)
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain
Alanine aminotransferase increased
Arthralgia (joint pain)
Aspartate aminotransferase increased
Bereavement reaction

What are the existing conditions these people have? *

Pain: 21 people, 24.71%
Depression: 7 people, 8.24%
High Blood Pressure: 6 people, 7.06%
High Blood Cholesterol: 6 people, 7.06%
Nausea And Vomiting: 5 people, 5.88%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 5.88%
Glossitis (infection of tongue with soreness): 5 people, 5.88%
Dissociative Disorder: 5 people, 5.88%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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