Glucotrol and Lactulose drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glucotrol (glipizide) and Lactulose (lactulose). Common drug interactions include anxiety among females and confusional state among males.
The phase IV clinical study analyzes what interactions people have when they take Glucotrol and Lactulose. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.
What is Glucotrol?
Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.
What is Lactulose?
Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
64 people who take Glucotrol and Lactulose together, and have interactions are studied.

What are the common drug interactions of Glucotrol and Lactulose, by gender? *:
female:
- Anxiety
- Back pain
- Blood culture positive
- Borderline glaucoma
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cellulitis (infection under the skin)
- Cystitis (inflammation of the wall of the bladder)
- Headache (pain in head)
- Inflammation
- Injury
male:
- Confusional state
- Hypertension (high blood pressure)
- Oedema (fluid collection in tissue)
- Weight increased
- Anaemia (lack of blood)
- Anxiety
- Bradycardia (abnormally slow heart action)
- Chest pain
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Coombs direct test positive
What are the common drug interactions of Glucotrol and Lactulose, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Acute psychosis (period of mentally unstable behaviour)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cellulitis (infection under the skin)
- Contusion (a type of hematoma of tissue in which capillaries)
- Diabetic foot infection
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Excoriation (to tear or wear off the skin of)
- Fall
- Incontinence (lack of moderation or self-control)
40-49:
- Abdominal discomfort
- Abnormal weight gain
- Affective disorder (mental disorder)
- Agitation (state of anxiety or nervous excitement)
- Anxiety
- Asthma
- Blood glucose increased
- Blood pressure increased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chest pain
50-59:
- Confusional state
- Cough
- Dizziness
- Drug ineffective
- Dry mouth
- Dyspnoea (difficult or laboured respiration)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Exercise tolerance decreased
- Fatigue (feeling of tiredness)
- Fluid overload (too much fluid in the blood)
60+:
- Hepatic failure (liver failure)
- Pain
- Anaemia (lack of blood)
- Anxiety
- Back pain
- Confusional state
- Dyspnoea (difficult or laboured respiration)
- Hepatitis (inflammation of the liver)
- Hypokalaemia (low potassium)
- Injury
What are the existing conditions these people have? *
- Pain: 5 people, 7.81%
- High Blood Pressure: 4 people, 6.25%
- High Blood Cholesterol: 4 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Glucotrol and Lactulose?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Glucotrol and Lactulose:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glucotrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lactulose:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glucotrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lactulose and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on glipizide and lactulose (the active ingredients of Glucotrol and Lactulose, respectively), and Glucotrol and Lactulose (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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