Glucovance and Trimox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glucovance (glyburide; metformin hydrochloride) and Trimox (amoxicillin). Common drug interactions include coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Glucovance and Trimox. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

What is Trimox?

Trimox has active ingredients of amoxicillin. eHealthMe is studying from 932 Trimox users. Check the latest studies of Trimox.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

11 people who take Glucovance and Trimox together, and have interactions are studied.

Glucovance and Trimox drug interactions.

What are the common drug interactions of Glucovance and Trimox, by gender? *:

female:

n/a

male:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Occult blood positive
Diabetes mellitus inadequate control
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Hypokalaemia (low potassium)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Glucovance and Trimox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Thrombosis (formation of a blood clot inside a blood vessel)
Bacterial infection
Blood pressure increased
Cardiovascular disorder (heart diseases)
Chest pain
Delusion of grandeur
Headache (pain in head)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)
Iliac artery occlusion (narrowing of an arterial segment between the aortic bifurcation and the groin)

60+:

Occult blood positive
Pneumonia
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Hypokalaemia (low potassium)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure acute (rapid kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 36.36%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 18.18%
Pain: 2 people, 18.18%
Infection: 2 people, 18.18%
Depression: 2 people, 18.18%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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