Glyburide and Fentanyl transdermal system drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glyburide (glyburide) and Fentanyl transdermal system (fentanyl). Common drug interactions include brain injury among females and kidney infection among males.

The phase IV clinical study analyzes what interactions people have when they take Glyburide and Fentanyl transdermal system. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Glyburide?

Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.

What is Fentanyl transdermal system?

Fentanyl transdermal system has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 5,728 Fentanyl transdermal system users. Check the latest studies of Fentanyl transdermal system.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

27 people who take Glyburide and Fentanyl transdermal system together, and have interactions are studied.

Glyburide and Fentanyl transdermal system drug interactions.

What are the common drug interactions of Glyburide and Fentanyl Transdermal System, by gender? *:

female:

Brain injury
Coma (state of unconsciousness lasting more than six hours)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Drug ineffective
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hepatic failure (liver failure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Pneumonia

male:

Kidney infection
Overdose
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Abasia (inability to walk)
Application site erythema (redness of the skin at application site)
Asthenia (weakness)
Blood cholesterol decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Coma (state of unconsciousness lasting more than six hours)
Diabetic complication

What are the common drug interactions of Glyburide and Fentanyl Transdermal System, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Brain injury
Coma (state of unconsciousness lasting more than six hours)
Hepatic failure (liver failure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Drug administration error
Drug effect increased
Dyspnoea (difficult or laboured respiration)

50-59:

Application site erythema (redness of the skin at application site)
Drug effect decreased

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Pneumonia primary atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haemoglobin decreased
Lethargy (tiredness)
Sudden death
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Epistaxis (bleed from the nose)
Haemorrhage (bleeding)
Abdominal pain

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 25.93%
Depression: 5 people, 18.52%
Breakthrough Pain: 5 people, 18.52%
High Blood Cholesterol: 5 people, 18.52%
Back Pain: 4 people, 14.81%
Stress And Anxiety: 3 people, 11.11%
Multiple Allergies (allergy to multiple agents): 3 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
Asthma: 2 people, 7.41%
Chest Pain: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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