Glyburide and Paxil cr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glyburide (glyburide) and Paxil cr (paroxetine hydrochloride). Common drug interactions include respiratory failure among females and drug exposure during pregnancy among males.

The phase IV clinical study analyzes what interactions people have when they take Glyburide and Paxil cr. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Glyburide?

Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.

What is Paxil cr?

Paxil cr has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 8,322 Paxil cr users. Check the latest studies of Paxil cr.

On Jul, 10, 2026

25 people who take Glyburide and Paxil cr together, and have interactions are studied.

Glyburide and Paxil cr drug interactions.

What are the common drug interactions of Glyburide and Paxil Cr, by gender? *:

female:

Respiratory failure (inadequate gas exchange by the respiratory system)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Chest pain
Enuresis (repeated inability to control urination)
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Hyperglycaemia (high blood sugar)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Urinary hesitation (difficulty in beginning the flow of urine)

male:

Drug exposure during pregnancy
Pulmonary artery stenosis congenital (congenital -narrowing (stenosis) that occurs in the lung artery)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
Ageusia (loss of taste functions of the tongue)
Anosmia (partial or complete loss of the sense of smell)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Hemiplegia (paralysis of one side of the body)

What are the common drug interactions of Glyburide and Paxil Cr, by age (0-1 to 60+)? *:

0-1:

Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus inadequate control
Hyperglycaemia (high blood sugar)
Type 1 diabetes mellitus

40-49:

Angioedema (rapid swelling of the dermis)
Hereditary angioedema (recurrent episodes of severe swelling)
Infusion related reaction
Nausea (feeling of having an urge to vomit)
Swelling
Vomiting

50-59:

Chest pain
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Asthma
Dental caries
Dysfunctional uterine bleeding
Ear pain
Fatigue (feeling of tiredness)
Hyperglycaemia (high blood sugar)
Hypertension (high blood pressure)
Local swelling (swelling at the site of some application of substance or injury)

60+:

Cardiac failure congestive
Carotid artery stenosis (narrowing of carotid artery)
Coronary artery stenosis (narrowing of coronary artery)
Injury
Mitral valve calcification (calcium deposit in mitral valve)
Mitral valve incompetence (inefficient heart valve)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Femoral arterial stenosis (narrowing of artery of femur bone)
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)

What are the existing conditions these people have? *

Depression: 12 people, 48.00%
Postpartum Depression (depression suffered by a mother following childbirth): 7 people, 28.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 12.00%
High Blood Pressure: 3 people, 12.00%
High Blood Cholesterol: 3 people, 12.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 12.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 12.00%
Insomnia (sleeplessness): 2 people, 8.00%
Headache (pain in head): 2 people, 8.00%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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