Glyburide and Sumatriptan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glyburide (glyburide) and Sumatriptan (sumatriptan succinate). Common drug interactions include gastroenteritis among females and arterial insufficiency among males.
The phase IV clinical study analyzes what interactions people have when they take Glyburide and Sumatriptan. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Glyburide?
Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.
What is Sumatriptan?
Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.
11 people who take Glyburide and Sumatriptan together, and have interactions are studied.

What are the common drug interactions of Glyburide and Sumatriptan, by gender? *:
female:
- Gastroenteritis (inflammation of stomach and intestine)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hepatic steatosis (fatty liver disease)
- Hepatitis (inflammation of the liver)
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Herpes zoster
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
male:
- Arterial insufficiency (lack of enough blood flow through the arteries)
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
- Aspartate aminotransferase increased
- Blood glucose increased
- Confusional state
- Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
- Decreased appetite
- Dizziness
- Premature baby
- Pruritus (severe itching of the skin)
What are the common drug interactions of Glyburide and Sumatriptan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Acute respiratory distress syndrome
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cardiac failure congestive
- Chronic kidney disease
- Coma (state of unconsciousness lasting more than six hours)
- Drug clearance decreased
- Feeding disorder (when children refuse to eat certain food groups)
- Nasopharyngitis (inflammation of the nasopharynx)
- Pneumonia
- Renal failure (kidney dysfunction)
50-59:
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dizziness
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Gastroenteritis (inflammation of stomach and intestine)
- Herpes zoster
- Injection site abscess
- Injection site cellulitis (injection site inflammation)
- Pruritus (severe itching of the skin)
- Sepsis (a severe blood infection that can lead to organ failure and death)
60+:
- Depression
- Neuropathy peripheral (surface nerve damage)
- Malaise (a feeling of general discomfort or uneasiness)
- Muscle spasms (muscle contraction)
- Myalgia (muscle pain)
- Oedema (fluid collection in tissue)
- Sleep disorder
- Weight increased
- Abdominal mass (localized enlargement or swelling in the human abdomen)
- Affect lability (emotional incontinence)
What are the existing conditions these people have? *
- Thyroid Neoplasm (tumour of thyroid): 2 people, 18.18%
- Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 18.18%
- Depression: 2 people, 18.18%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 18.18%
- High Blood Pressure: 1 person, 9.09%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 9.09%
- Cluster Headache (one-sided head pain with tearing): 1 person, 9.09%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
- High Blood Cholesterol: 1 person, 9.09%
- Immunodeficiency Common Variable: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Glyburide and Sumatriptan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Glyburide (38,448 reports)
- Sumatriptan (18,159 reports)
Browse all drug interactions of Glyburide and Sumatriptan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glyburide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sumatriptan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glyburide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sumatriptan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on glyburide and sumatriptan succinate (the active ingredients of Glyburide and Sumatriptan, respectively), and Glyburide and Sumatriptan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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