Glyburide and Tasigna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glyburide (glyburide) and Tasigna (nilotinib hydrochloride monohydrate). Common drug interactions include atelectasis among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Glyburide and Tasigna. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Glyburide?

Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.

What is Tasigna?

Tasigna has active ingredients of nilotinib hydrochloride monohydrate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 31,535 Tasigna users. Check the latest studies of Tasigna.



On Jul, 31, 2026

48 people who take Glyburide and Tasigna together, and have interactions are studied.

Glyburide and Tasigna drug interactions.

What are the common drug interactions of Glyburide and Tasigna, by gender? *:

female:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  4. Atrioventricular block first degree (heart block first degree)
  5. Bloody discharge
  6. Cardiac hypertrophy (thickening of the heart muscle)
  7. Cardiomegaly (increased size of heart than normal)
  8. Concomitant disease progression (progress in accompanying disease)
  9. Cough
  10. Dyspnoea exertional (breathlessness or shortness of breath)

male:

  1. Pain in extremity
  2. Cardiac failure congestive
  3. Aortic valve calcification
  4. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  8. Atrioventricular block first degree (heart block first degree)
  9. Bloody discharge
  10. Candidiasis (candidiasis or thrush is a fungal infection)

What are the common drug interactions of Glyburide and Tasigna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain upper
  2. Diarrhoea
  3. Nausea (feeling of having an urge to vomit)
  4. Pancreatitis acute (sudden inflammation of pancreas)
  5. Vomiting
  6. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  7. Drug ineffective
  8. Encephalitis herpes (inflammation of the brain due to herpes infection)
  9. Hypertension (high blood pressure)
  10. Memory impairment

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal distension
  2. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  3. Aortic valve calcification
  4. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  9. Atrioventricular block first degree (heart block first degree)
  10. Bloody discharge

50-59:

  1. Wound
  2. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  3. Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
  4. Anaemia (lack of blood)
  5. Arteriosclerosis obliterans (thickening and hardening of arteries)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Blood glucose increased
  8. Constipation
  9. Eye haemorrhage (bleeding in the eye)
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

60+:

  1. Cardiac failure congestive
  2. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  3. Bloody discharge
  4. Candidiasis (candidiasis or thrush is a fungal infection)
  5. Cardiac hypertrophy (thickening of the heart muscle)
  6. Cardiomegaly (increased size of heart than normal)
  7. Concomitant disease progression (progress in accompanying disease)
  8. Cough
  9. Dyspnoea exertional (breathlessness or shortness of breath)
  10. Electrocardiogram pq interval prolonged

What are the existing conditions these people have? *

  1. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 35 people, 72.92%
  2. High Blood Pressure: 7 people, 14.58%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.33%
  4. Joint Pain: 3 people, 6.25%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.25%
  6. High Blood Cholesterol: 3 people, 6.25%
  7. Constipation: 3 people, 6.25%
  8. Back Pain: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Glyburide and Tasigna?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glyburide and Tasigna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glyburide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tasigna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glyburide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tasigna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on glyburide and nilotinib hydrochloride monohydrate (the active ingredients of Glyburide and Tasigna, respectively), and Glyburide and Tasigna (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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