Glycine and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glycine (glycine) and Keppra (levetiracetam). Common drug interactions include accident among females and somnolence among males.

The phase IV clinical study analyzes what interactions people have when they take Glycine and Keppra. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Glycine?

Glycine has active ingredients of glycine. eHealthMe is studying from 1,063 Glycine users. Check the latest studies of Glycine.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.



On Jul, 14, 2026

16 people who take Glycine and Keppra together, and have interactions are studied.

Glycine and Keppra drug interactions.

What are the common drug interactions of Glycine and Keppra, by gender? *:

female:

  1. Accident
  2. Headache (pain in head)
  3. Depressed level of consciousness
  4. Drug ineffective
  5. Oculomucocutaneous syndrome (a condition characterized by keratoconjunctivitis sicca and by scarring, fibrosis, metaplasia, and shrinkage of the conjunctiva;)
  6. Pneumonia
  7. Rash
  8. Sopor (sleep)
  9. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  10. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

male:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Arthralgia (joint pain)
  3. Hyperkeratosis (thickening of the outer layer of the skin)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Intra-abdominal haemorrhage (intra-abdominal bleeding)
  6. Joint contracture (a permanent shortening of a muscle or joint)
  7. Joint range of motion decreased (disease of joint movement)
  8. Mobility decreased (ability to move is reduced)
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

What are the common drug interactions of Glycine and Keppra, by age (0-1 to 60+)? *:

0-1:

  1. Feeding disorder (when children refuse to eat certain food groups)
  2. Maternal exposure during pregnancy (use of substance during pregnancy)
  3. Premature baby
  4. Somnolence (a state of near-sleep, a strong desire for sleep)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood creatine phosphokinase increased
  2. Initial insomnia (feeling of inadequate or poor-quality sleep)
  3. Insomnia (sleeplessness)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

  1. Drug ineffective
  2. Hepatitis c
  3. Intra-abdominal haemorrhage (intra-abdominal bleeding)
  4. Oculomucocutaneous syndrome (a condition characterized by keratoconjunctivitis sicca and by scarring, fibrosis, metaplasia, and shrinkage of the conjunctiva;)
  5. Abdominal compartment syndrome (increased pressure in abdomen)

50-59:

  1. Arthralgia (joint pain)
  2. Deformity (disfigurement)
  3. Mobility decreased (ability to move is reduced)
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  6. Oedema (fluid collection in tissue)
  7. Oedema peripheral (superficial swelling)
  8. Pain
  9. Pain in extremity
  10. Pain of skin

60+:

n/a

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 25.00%
  2. Nuclear Magnetic Resonance Imaging Brain: 3 people, 18.75%
  3. High Blood Pressure: 3 people, 18.75%
  4. Hepatitis C: 3 people, 18.75%
  5. Disease Complication: 3 people, 18.75%
  6. Hiv Infection: 3 people, 18.75%
  7. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 3 people, 18.75%
  8. Agitation (state of anxiety or nervous excitement): 2 people, 12.50%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 12.50%
  10. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glycine and Keppra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glycine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Keppra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glycine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Keppra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glycine and levetiracetam (the active ingredients of Glycine and Keppra, respectively), and Glycine and Keppra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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