Glycolax and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glycolax (polyethylene glycol 3350) and Lidoderm (lidocaine). Common drug interactions include gastrointestinal motility disorder among females and application site reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Glycolax and Lidoderm. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Glycolax?

Glycolax has active ingredients of polyethylene glycol 3350. eHealthMe is studying from 2,036 Glycolax users. Check the latest studies of Glycolax.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

On Aug, 06, 2026

55 people who take Glycolax and Lidoderm together, and have interactions are studied.

Glycolax and Lidoderm drug interactions.

What are the common drug interactions of Glycolax and Lidoderm, by gender? *:

female:

Gastrointestinal motility disorder (abnormal intestinal contractions)
Hyperkalaemia (damage to or disease of the kidney)
Lumbar radiculopathy (radicular pain in the low back and legs)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Neuroma (tumour of nerve tissue)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in extremity
Piriformis syndrome (neuromuscular disorder that occurs when the sciatic nerve is compressed)
Post lumbar puncture syndrome

male:

Application site reaction
Chronic kidney disease
Renal impairment (severely reduced kidney function)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal pain upper
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anaemia (lack of blood)
Body height decreased
Cataract (clouding of the lens inside the eye)

What are the common drug interactions of Glycolax and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Ataxia (loss of full control of bodily movements)
Dizziness
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Periodic limb movement disorder
Restless legs syndrome (a powerful urge to move your legs)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

Anaemia (lack of blood)
Asthenia (weakness)
Asthma
Decreased appetite
Drug ineffective
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperglycaemia (high blood sugar)
Impaired gastric emptying

50-59:

Faecal incontinence (a lack of control over passing stool)
Gout (uric acid crystals building up in the body)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Hypoaesthesia (reduced sense of touch or sensation)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Hypoxia (low oxygen in tissues)
Implant site erosion
Lymphoedema (localized fluid retention and tissue swelling)
Muscle spasms (muscle contraction)

60+:

Constipation
Fall
Arthralgia (joint pain)
Balance disorder
Blood glucose increased
Cardiac arrest
Carotid artery aneurysm (a bulging or ballooning in the wall of a blood vessel)
Cellulitis (infection under the skin)
Diarrhoea
Dizziness

What are the existing conditions these people have? *

Constipation: 12 people, 21.82%
High Blood Pressure: 11 people, 20.00%
Stress And Anxiety: 10 people, 18.18%
Depression: 10 people, 18.18%
Nausea (feeling of having an urge to vomit): 10 people, 18.18%
High Blood Cholesterol: 9 people, 16.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 14.55%
Type 2 Diabetes: 7 people, 12.73%
Insomnia (sleeplessness): 5 people, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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