Glycolax and Sinemet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glycolax (polyethylene glycol 3350) and Sinemet (carbidopa; levodopa). Common drug interactions include stress among females and memory impairment among males.
The phase IV clinical study analyzes what interactions people have when they take Glycolax and Sinemet. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.
What is Glycolax?
Glycolax has active ingredients of polyethylene glycol 3350. eHealthMe is studying from 2,036 Glycolax users. Check the latest studies of Glycolax.
What is Sinemet?
Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.
54 people who take Glycolax and Sinemet together, and have interactions are studied.

What are the common drug interactions of Glycolax and Sinemet, by gender? *:
female:
- Stress
- Urinary tract infection
- Abdominal pain
- Adverse drug reaction
- Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
- Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Asthma
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
male:
- Memory impairment
- Confusional state
- Blood bilirubin increased
- Fall
- Fatigue (feeling of tiredness)
- Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Small intestinal obstruction (blockage in small intestine)
- Chest pain
- Constipation
What are the common drug interactions of Glycolax and Sinemet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Colonic polyp (extra part of colon tissue grow in intestine)
- Confusional state
- Conjunctivitis (pink eye)
- Constipation
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Coronary artery thrombosis (clot formation in coronary artery)
- Cough
- Cystitis glandularis (forming a timorous lesion with blueberry spots in the urinary bladder)
- Deafness
- Decreased appetite
50-59:
- Cold sweat
- Drug ineffective
- Facial spasm (involuntary muscle contractions face)
- Fall
- Gait disturbance
- Hallucination (an experience involving the perception of something not present)
- Hyperglycaemia (high blood sugar)
- Hypokalaemia (low potassium)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Insomnia (sleeplessness)
60+:
- Confusional state
- Dyskinesia (abnormality or impairment of voluntary movement)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Small intestinal obstruction (blockage in small intestine)
- Fall
- Death
- Hallucination (an experience involving the perception of something not present)
- Hypertension (high blood pressure)
- Abdominal pain upper
- Device occlusion
What are the existing conditions these people have? *
- Hallucinations (sensations that appear real but are created by your mind): 14 people, 25.93%
- Delusion (a false belief or opinion): 12 people, 22.22%
- Pain: 9 people, 16.67%
- Constipation: 7 people, 12.96%
- Dyskinesia (abnormality or impairment of voluntary movement): 5 people, 9.26%
- Depression: 5 people, 9.26%
- Stress And Anxiety: 4 people, 7.41%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 7.41%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.41%
- Dyspnea (difficult or laboured breathing): 4 people, 7.41%
* Approximation only. Some reports may have incomplete information.
Do you take Glycolax and Sinemet?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Glycolax and Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glycolax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glycolax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sinemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on polyethylene glycol 3350 and carbidopa; levodopa (the active ingredients of Glycolax and Sinemet, respectively), and Glycolax and Sinemet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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