Glyxambi and Gabapentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glyxambi (empagliflozin; linagliptin) and Gabapentin (gabapentin). Common drug interactions include sinus congestion among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Glyxambi and Gabapentin. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Glyxambi?

Glyxambi has active ingredients of empagliflozin; linagliptin. eHealthMe is studying from 1,835 Glyxambi users. Check the latest studies of Glyxambi.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,987 Gabapentin users. Check the latest studies of Gabapentin.

On Aug, 02, 2026

72 people who take Glyxambi and Gabapentin together, and have interactions are studied.

Glyxambi and Gabapentin drug interactions.

What are the common drug interactions of Glyxambi and Gabapentin, by gender? *:

female:

Sinus congestion (blockage of sinus)
Sinusitis (inflammation of sinus)
Stiff person syndrome
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tenderness (pain or discomfort when an affected area is touched)
Blood glucose increased
Constipation
Decreased appetite
Fungal infection
Glycosylated haemoglobin increased

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Fatigue (feeling of tiredness)
Glycosylated haemoglobin increased
Hemiplegia (paralysis of one side of the body)
Visual field defect
Blindness unilateral
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Eye infection
Fibromyalgia (a long-term condition which causes pain all over the body)
Hypersomnia (excessive daytime sleepiness (eds))

What are the common drug interactions of Glyxambi and Gabapentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Balance disorder
Blindness unilateral
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Headache (pain in head)
Hypersomnia (excessive daytime sleepiness (eds))
Hypoacusis (loss of hearing)
Hypoaesthesia (reduced sense of touch or sensation)

20-29:

n/a

30-39:

Fatigue (feeling of tiredness)
Food poisoning (poison in food)
Gastrointestinal infection (infection of stomach and intestine)
Headache (pain in head)
Myalgia (muscle pain)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Otitis media (inflammation of the middle ear)
Poor venous access

40-49:

Abdominal pain
Pancreatitis (inflammation of pancreas)
Abdominal pain upper
Abscess neck (neck abscesses)
Depression
Erythema (redness of the skin)
Eye infection
Eye pain
Fatigue (feeling of tiredness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Hypokinesia (decreased bodily movement)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Injury
Limb discomfort (discomfort in leg)
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Memory impairment
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)

60+:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abdominal discomfort
Hemiplegia (paralysis of one side of the body)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Visual field defect
Eye infection
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Insomnia (sleeplessness)
Arthralgia (joint pain)

What are the existing conditions these people have? *

Type 2 Diabetes: 13 people, 18.06%
Diabetes: 12 people, 16.67%
Neuropathy Peripheral (surface nerve damage): 8 people, 11.11%
High Blood Pressure: 7 people, 9.72%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.33%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 6.94%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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