Gocovri and Prozac drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gocovri (amantadine hydrochloride) and Prozac (fluoxetine hydrochloride). Common drug interactions include hip arthroplasty among females and balance disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Gocovri and Prozac. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Gocovri?
Gocovri has active ingredients of amantadine hydrochloride. eHealthMe is studying from 2,662 Gocovri users. Check the latest studies of Gocovri.
What is Prozac?
Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.
17 people who take Gocovri and Prozac together, and have interactions are studied.

What are the common drug interactions of Gocovri and Prozac, by gender? *:
female:
- Hip arthroplasty
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Throat irritation
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Chromatopsia (visual defect in which colourless objects appear to be tinged with colour)
- Drooling (drop saliva uncontrollably from the mouth)
- Dysphemia (stammering or stuttering)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Fatigue (feeling of tiredness)
- Freezing phenomenon
male:
- Balance disorder
- Deep brain stimulation
- Dyskinesia (abnormality or impairment of voluntary movement)
- Fall
- Feeling hot
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
What are the common drug interactions of Gocovri and Prozac, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Dyskinesia (abnormality or impairment of voluntary movement)
- Constipation
- Nerve compression
- Neuropathy peripheral (surface nerve damage)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pain
- Pain in extremity
- Spondylitis (an inflammation of the vertebra with spinal cord involvement)
- Ulcer
- Agitation (state of anxiety or nervous excitement)
What are the existing conditions these people have? *
- Dyskinesia (abnormality or impairment of voluntary movement): 11 people, 64.71%
- Parkinson's Disease: 10 people, 58.82%
- On And Off Phenomenon: 1 person, 5.88%
- Movement - Uncontrolled Or Slow: 1 person, 5.88%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Gocovri and Prozac?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Gocovri and Prozac:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gocovri:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Prozac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gocovri and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prozac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Yang Y, Teja S, Baig K, "Bilateral corneal edema associated with amantadine", Canadian Medical Association Journal, 2015 Oct .
- Cattoni J, Parekh R, "Acute respiratory distress syndrome: A rare presentation of amantadine toxicity", The American journal of case reports, 2012 Jan .
- Yang Y, Teja S, Baig K, "Bilateral corneal edema associated with amantadine", Canadian Medical Association Journal, 2015 Oct .
- Cattoni J, Parekh R, "Acute respiratory distress syndrome: A rare presentation of amantadine toxicity", The American journal of case reports, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on amantadine hydrochloride and fluoxetine hydrochloride (the active ingredients of Gocovri and Prozac, respectively), and Gocovri and Prozac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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