Golytely and Colace drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Golytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous) and Colace (docusate ). Common drug interactions include chest pain among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Golytely and Colace. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Golytely?
Golytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous. eHealthMe is studying from 907 Golytely users. Check the latest studies of Golytely.
What is Colace?
Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.
41 people who take Golytely and Colace together, and have interactions are studied.

What are the common drug interactions of Golytely and Colace, by gender? *:
female:
- Chest pain
- Dehydration (dryness resulting from the removal of water)
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemorrhage (bleeding)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Hypersensitivity
- Hypoaesthesia (reduced sense of touch or sensation)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Anaemia (lack of blood)
- Blood pressure increased
- Chest pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Decreased appetite
- Dizziness postural
- Gait disturbance
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
What are the common drug interactions of Golytely and Colace, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Gastroenteritis (inflammation of stomach and intestine)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Pneumonia
30-39:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Nephropathy (damage to or disease of a kidney)
40-49:
- Anxiety
- Pain in extremity
- Chest pain
- Dehydration (dryness resulting from the removal of water)
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Haemorrhage (bleeding)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Hypoaesthesia (reduced sense of touch or sensation)
50-59:
- Nausea (feeling of having an urge to vomit)
- Renal tubular necrosis (death of kidney tubules)
- Suicide attempt
- Therapeutic response unexpected
- Viral test positive
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
60+:
- Pain
- Abdominal distension
- Vision blurred
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood pressure increased
- Chest pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Decreased appetite
- Dizziness
What are the existing conditions these people have? *
- Pain: 16 people, 39.02%
- High Blood Pressure: 10 people, 24.39%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 14.63%
- Stress And Anxiety: 6 people, 14.63%
- Nausea (feeling of having an urge to vomit): 6 people, 14.63%
- Diabetes: 5 people, 12.20%
- High Blood Cholesterol: 4 people, 9.76%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 9.76%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.32%
- Muscle Spasms (muscle contraction): 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Golytely and Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Golytely:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Golytely and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous and docusate (the active ingredients of Golytely and Colace, respectively), and Golytely and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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