Golytely and Cymbalta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Golytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous) and Cymbalta (duloxetine hydrochloride). Common drug interactions include constipation among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Golytely and Cymbalta. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Golytely?
Golytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous. eHealthMe is studying from 907 Golytely users. Check the latest studies of Golytely.
What is Cymbalta?
Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.
21 people who take Golytely and Cymbalta together, and have interactions are studied.

What are the common drug interactions of Golytely and Cymbalta, by gender? *:
female:
- Constipation
- Alopecia (absence of hair from areas of the body)
- Colonoscopy
- Diarrhoea
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Surgery
- Drug dependence
- Impaired work ability
- Abdominal pain
- Blood magnesium decreased
male:
- Chronic kidney disease
- Abdominal pain
- Hyperhidrosis (abnormally increased sweating)
- Melaena (the passage of black, tarry stools)
- Pain
- Renal failure (kidney dysfunction)
- Weight decreased
- Adverse event
- Chest discomfort
- Constipation
What are the common drug interactions of Golytely and Cymbalta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Chronic kidney disease
- Constipation
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Oedema peripheral (superficial swelling)
- Renal failure (kidney dysfunction)
50-59:
- Constipation
- Colonoscopy
- Diarrhoea
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Blood magnesium decreased
- Blood potassium decreased
- Blood sodium decreased
- Breast cancer
- Chemotherapy
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
60+:
- Alopecia (absence of hair from areas of the body)
- Chronic kidney disease
- Emotional distress
- Essential hypertension (primary hypertension)
- Faeces hard
- Hyperhidrosis (abnormally increased sweating)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Melaena (the passage of black, tarry stools)
- Memory impairment
- Pain
What are the existing conditions these people have? *
- Pain: 6 people, 28.57%
- Constipation: 6 people, 28.57%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 23.81%
- High Blood Pressure: 4 people, 19.05%
- Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 19.05%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 14.29%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 14.29%
- Nausea (feeling of having an urge to vomit): 3 people, 14.29%
- Nausea And Vomiting: 3 people, 14.29%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Golytely and Cymbalta?
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Golytely and Cymbalta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Golytely:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cymbalta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Golytely and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cymbalta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous and duloxetine hydrochloride (the active ingredients of Golytely and Cymbalta, respectively), and Golytely and Cymbalta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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