Granix and Zide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Granix (tbo-filgrastim) and Zide (hydrochlorothiazide). Common drug interactions include feeling jittery among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Granix and Zide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Granix?
Granix has active ingredients of tbo-filgrastim. eHealthMe is studying from 897 Granix users. Check the latest studies of Granix.
What is Zide?
Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.
17 people who take Granix and Zide together, and have interactions are studied.

What are the common drug interactions of Granix and Zide, by gender? *:
female:
- Feeling jittery
- Cellulitis (infection under the skin)
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Sleep disorder
male:
- Fatigue (feeling of tiredness)
- Neuropathy peripheral (surface nerve damage)
- Blood glucose decreased
- Blood pressure decreased
- Cardiac failure
- Contusion (a type of hematoma of tissue in which capillaries)
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Drug hypersensitivity
- Fall
What are the common drug interactions of Granix and Zide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Epistaxis (bleed from the nose)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
60+:
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Fall
- Feeling jittery
- Gait disturbance
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 12 people, 70.59%
- Quit Smoking: 3 people, 17.65%
- Pain: 3 people, 17.65%
- Neuropathy Peripheral (surface nerve damage): 3 people, 17.65%
- Hypokalemia (low potassium): 3 people, 17.65%
- Hyperglycemia (high blood sugar): 3 people, 17.65%
- Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 17.65%
- Lymphoma (cancer that begins in immune system cells): 2 people, 11.76%
- Infusion Related Reaction: 2 people, 11.76%
- Hypergammaglobulinaemia (elevated levels of gamma globulin): 2 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Granix and Zide?
- Personalize this study to your gender, age, symptoms and drugs
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- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Granix and Zide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Granix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Granix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tbo-filgrastim and hydrochlorothiazide (the active ingredients of Granix and Zide, respectively), and Granix and Zide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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