Guaifenesin and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Guaifenesin (guaifenesin) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include pharyngeal mass among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Guaifenesin and Pradaxa. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

100 people who take Guaifenesin and Pradaxa together, and have interactions are studied.

Guaifenesin and Pradaxa drug interactions.

What are the common drug interactions of Guaifenesin and Pradaxa, by gender? *:

female:

Pharyngeal mass
Retching (strong involuntary effort to vomit)
Skin fissures (a crack in the skin)
Sleep disorder
Urticaria (rash of round, red welts on the skin that itch intensely)
Vertigo
Vision blurred
Vomiting
Coagulopathy (blood's ability to clot is impaired)
Haematochezia (passage of stools containing blood)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anaemia (lack of blood)
Pleural effusion (water on the lungs)
Cerebral haemorrhage (bleeding within the brain)
Fall
Pneumonia
Retinal haemorrhage (bleeding from retina)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety

What are the common drug interactions of Guaifenesin and Pradaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

50-59:

Coagulopathy (blood's ability to clot is impaired)
Epistaxis (bleed from the nose)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Multiple fractures
Renal failure (kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anaemia (lack of blood)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Device occlusion
Gait disturbance
Decreased appetite
Headache (pain in head)
Hypertension (high blood pressure)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Pain: 20 people, 20.00%
High Blood Pressure: 15 people, 15.00%
Constipation: 13 people, 13.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 10.00%
Chest Pain: 10 people, 10.00%
Insomnia (sleeplessness): 9 people, 9.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 9.00%
Fever: 7 people, 7.00%
Dyspnea (difficult or laboured breathing): 7 people, 7.00%
Stress And Anxiety: 7 people, 7.00%

* Approximation only. Some reports may have incomplete information.

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