Guaifenesin and Trimox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Guaifenesin (guaifenesin) and Trimox (amoxicillin). Common drug interactions include tardive dyskinesia among females and completed suicide among males.

The phase IV clinical study analyzes what interactions people have when they take Guaifenesin and Trimox. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.

What is Trimox?

Trimox has active ingredients of amoxicillin. eHealthMe is studying from 932 Trimox users. Check the latest studies of Trimox.



On Aug, 04, 2026

12 people who take Guaifenesin and Trimox together, and have interactions are studied.

Guaifenesin and Trimox drug interactions.

What are the common drug interactions of Guaifenesin and Trimox, by gender? *:

female:

  1. Tardive dyskinesia (a disorder that involves involuntary movements)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Asthma
  4. Confusional state
  5. Drug abuser
  6. Drug dependence
  7. Drug hypersensitivity
  8. Drug ineffective
  9. Dyskinesia (abnormality or impairment of voluntary movement)
  10. Emotional disorder

male:

  1. Completed suicide (act of taking one's own life)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Abdominal pain upper
  4. Anger
  5. Arrhythmia (irregular heartbeat)
  6. Asthma
  7. Blood pressure increased
  8. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  9. Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
  10. Cardiac disorder

What are the common drug interactions of Guaifenesin and Trimox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Completed suicide (act of taking one's own life)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Alcohol poisoning
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Drug ineffective
  6. Fall
  7. Anger
  8. Fear
  9. Feeling cold
  10. Gun shot wound

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal injury (kidney injury)
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Emotional disorder
  5. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  6. Injury
  7. Renal failure (kidney dysfunction)
  8. Renal transplant
  9. Tardive dyskinesia (a disorder that involves involuntary movements)

50-59:

  1. Abdominal distension
  2. Abdominal pain
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Arrhythmia (irregular heartbeat)
  5. Blood pressure increased
  6. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  7. Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
  8. Cardiac disorder
  9. Chest pain
  10. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)

60+:

  1. Abdominal distension
  2. Abdominal pain upper
  3. Drug hypersensitivity
  4. Nausea (feeling of having an urge to vomit)
  5. Rectal bleeding (bleeding from rectum)
  6. Taste disturbance
  7. Weakness

What are the existing conditions these people have? *

  1. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 25.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
  3. Sinusitis (inflammation of sinus): 2 people, 16.67%
  4. Pain: 2 people, 16.67%
  5. Renal Disorder (kidney disease): 1 person, 8.33%
  6. Multiple Allergies (allergy to multiple agents): 1 person, 8.33%
  7. Infection: 1 person, 8.33%
  8. High Blood Pressure: 1 person, 8.33%
  9. Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Guaifenesin and Trimox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Guaifenesin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trimox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Guaifenesin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trimox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin and amoxicillin (the active ingredients of Guaifenesin and Trimox, respectively), and Guaifenesin and Trimox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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