Halcion and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Halcion (triazolam) and Codeine (codeine sulfate). Common drug interactions include headache among females and gingival abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Halcion and Codeine. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Halcion?

Halcion has active ingredients of triazolam. It is often used in insomnia. eHealthMe is studying from 8,268 Halcion users. Check the latest studies of Halcion.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

On Jan, 31, 2026

38 people who take Halcion and Codeine together, and have interactions are studied.

What are the common drug interactions of Halcion and Codeine, by gender? *:

female:

Headache (pain in head)
Constipation
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Decreased appetite
Diarrhoea
Myalgia (muscle pain)
Neuralgia (pain in one or more nerves)
Pain in extremity
Pain in jaw

male:

Gingival abscess (pus in gums)
Gingivitis (inflammation of gums)
Arthralgia (joint pain)
Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
Death
Fall
Hypotension (abnormally low blood pressure)
Joint effusion (presence of extra fluid in joint covering)
Myositis (inflammation of the muscles)
Nephrolithiasis (calculi in the kidneys)

What are the common drug interactions of Halcion and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Gingival abscess (pus in gums)
Gingivitis (inflammation of gums)
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Oral herpes (viral infection of mouth)
Infection
Candida sepsis (candida in blood stream)
Respiratory failure (inadequate gas exchange by the respiratory system)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Arthralgia (joint pain)

30-39:

Anaemia (lack of blood)
Constipation
Pruritus (severe itching of the skin)
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug abuse

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
Overdose
Pneumonia

50-59:

Decreased appetite
Diarrhoea
Myalgia (muscle pain)
Neuralgia (pain in one or more nerves)
Pain in extremity
Pain in jaw
Palpitations (feelings or sensations that your heart is pounding or racing)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Vitreous haemorrhage (intraocular (inside the eye) bleeding)
Drug hypersensitivity

60+:

Drug hypersensitivity
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
Fall
Nephrolithiasis (calculi in the kidneys)
Urinary retention postoperative

What are the existing conditions these people have? *

Constipation: 12 people, 31.58%
Familial Mediterranean Fever (genetic disease recurring attacks of abdominal pain, fever, pleurisy, arthritis, and rash): 5 people, 13.16%
Asthma: 5 people, 13.16%
Lung Cancer - Non-Small Cell (lung cancer): 5 people, 13.16%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 13.16%
Allergic Rhinitis: 4 people, 10.53%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 10.53%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 10.53%
Nausea (feeling of having an urge to vomit): 4 people, 10.53%
Headache (pain in head): 4 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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