Haldol and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Haldol (haloperidol) and Buscopan (hyoscine butylbromide). Common drug interactions include sepsis among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Haldol and Buscopan. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Haldol?

Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 23,102 Haldol users. Check the latest studies of Haldol.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.



On Jul, 16, 2026

33 people who take Haldol and Buscopan together, and have interactions are studied.

Haldol and Buscopan drug interactions.

What are the common drug interactions of Haldol and Buscopan, by gender? *:

female:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  3. Subcutaneous nodule
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Nausea (feeling of having an urge to vomit)
  6. General physical health deterioration (weak health status)
  7. Vomiting
  8. Abdominal pain
  9. Back pain
  10. Acquired porphyria (group of disorders that result in a build up of chemicals called porphyrins in the body)

male:

  1. Vomiting
  2. Aphasia (damage to the parts of the brain that control language)
  3. Diaphragmatic disorder
  4. Diarrhoea
  5. Nausea (feeling of having an urge to vomit)
  6. Renal failure (kidney dysfunction)
  7. Urinary retention (the inability to completely or partially empty the bladder)
  8. Urinary tract infection
  9. Blood pressure decreased
  10. Depressed level of consciousness

What are the common drug interactions of Haldol and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Dysarthria (speech disorder)
  2. Galactorrhoea (secretion of breast milk in men)
  3. Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
  4. Muscle rigidity (muscle stiffness)
  5. Salivary hypersecretion (excess saliva secretion)

20-29:

n/a

30-39:

  1. Aphasia (damage to the parts of the brain that control language)
  2. Asthenia (weakness)
  3. Dysphemia (stammering or stuttering)
  4. Gait disturbance
  5. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  6. Salivary hypersecretion (excess saliva secretion)
  7. Sedation
  8. Vomiting
  9. Speech disorder

40-49:

  1. Diaphragmatic disorder
  2. Diarrhoea
  3. Nausea (feeling of having an urge to vomit)
  4. Renal failure (kidney dysfunction)
  5. Urinary retention (the inability to completely or partially empty the bladder)
  6. Urinary tract infection
  7. Vomiting
  8. Fatigue (feeling of tiredness)
  9. Renal disorder (kidney disease)

50-59:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. General physical health deterioration (weak health status)
  4. Pneumonia influenzal (the flu with pneumonia)
  5. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  6. Blood pressure decreased
  7. Cardiac arrest
  8. Depressed level of consciousness
  9. Lung disorder (lung disease)
  10. Muscle atrophy (a decrease in the mass of the muscle)

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Abdominal pain
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Diarrhoea
  5. General physical health deterioration (weak health status)
  6. Liver injury
  7. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  8. Vertigo
  9. Pelvic pain
  10. Anaemia (lack of blood)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 9 people, 27.27%
  2. Pain: 6 people, 18.18%
  3. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 5 people, 15.15%
  4. Urinary Tract Infection Fungal: 3 people, 9.09%
  5. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 9.09%
  6. Constipation: 3 people, 9.09%
  7. Febrile Neutropenia (fever with reduced white blood cells): 3 people, 9.09%
  8. Fever: 3 people, 9.09%
  9. Abdominal Pain: 3 people, 9.09%
  10. H1n1 Influenza (flu (influenza), which is caused by virus influenza a (h1n1)): 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Haldol and Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Haldol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Haldol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buscopan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on haloperidol and hyoscine butylbromide (the active ingredients of Haldol and Buscopan, respectively), and Haldol and Buscopan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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