Hc and Imuran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hc (hydrocortisone) and Imuran (azathioprine). Common drug interactions include psoas abscess among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Hc and Imuran. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Hc?

Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.



On Jul, 07, 2026

20 people who take Hc and Imuran together, and have interactions are studied.

Hc and Imuran drug interactions.

What are the common drug interactions of Hc and Imuran, by gender? *:

female:

  1. Psoas abscess (collection of pus in the iliopsoas muscle compartment)
  2. Sinus congestion (blockage of sinus)
  3. Urinary tract infection
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Diarrhoea
  6. Poor venous access
  7. Dizziness
  8. Infusion site bruising
  9. Infusion site erythema (reddening of the skin at infusion site)
  10. Abdominal pain upper

male:

  1. Blood glucose increased
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Metastases to liver (cancer spreads to liver)
  4. Nerve injury
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Rectal abscess (pus in rectum)
  7. Renal cyst (kidney cyst)
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Tooth abscess (pus formation in tooth)
  10. Abdominal hernia

What are the common drug interactions of Hc and Imuran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Psoas abscess (collection of pus in the iliopsoas muscle compartment)

40-49:

n/a

50-59:

  1. Vomiting
  2. Wound dehiscence (a surgical incision reopens either internally or externally)
  3. Blood glucose increased
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Colon cancer
  6. Colon cancer stage iii
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  9. Facet joint syndrome (problem with movement of the facet joints of the spine)
  10. Intervertebral disc protrusion (spinal disc protrusion)

60+:

  1. Diarrhoea
  2. Dizziness
  3. Systolic hypertension (an elevated systolic blood pressure)
  4. Throat irritation
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Asthenia (weakness)
  7. Erythema (redness of the skin)
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Infusion site mass

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 10 people, 50.00%
  2. Immunodeficiency: 10 people, 50.00%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 10.00%
  4. Sleep Disorder: 2 people, 10.00%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
  6. Iron Deficiency: 2 people, 10.00%
  7. Diarrhea: 2 people, 10.00%
  8. Chest Pain: 2 people, 10.00%
  9. Abdominal Pain: 2 people, 10.00%
  10. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hc and Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imuran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone and azathioprine (the active ingredients of Hc and Imuran, respectively), and Hc and Imuran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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