Hc and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hc (hydrocortisone) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include headache among females and dysphagia among males.

The phase IV clinical study analyzes what interactions people have when they take Hc and Valacyclovir. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Hc?

Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 09, 2026

19 people who take Hc and Valacyclovir together, and have interactions are studied.

What are the common drug interactions of Hc and Valacyclovir, by gender? *:

female:

Headache (pain in head)
Hypermagnesaemia (an electrolyte disturbance in which there is an abnormally elevated level of magnesium in the blood)
Joint injury
Joint swelling
Lymphoedema (localized fluid retention and tissue swelling)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Neutropenia (an abnormally low number of neutrophils)
Skin exfoliation (removal of the oldest dead skin cells)
Skin wrinkling (wrinkle on skin)

male:

Dysphagia (a condition in which swallowing is difficult or painful)
Febrile neutropenia (fever with reduced white blood cells)
Hypersensitivity

What are the common drug interactions of Hc and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Aphonia (inability to produce voice)
Apnoea (suspension of external breathing)
Blood folate increased
Blood sodium increased
Carbon dioxide decreased
Constipation
Cough
Depression
Dyspnoea (difficult or laboured respiration)

50-59:

n/a

60+:

Hypoacusis (loss of hearing)
Alopecia (absence of hair from areas of the body)
Joint swelling
Lymphoedema (localized fluid retention and tissue swelling)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Neutropenia (an abnormally low number of neutrophils)
Skin exfoliation (removal of the oldest dead skin cells)
Skin wrinkling (wrinkle on skin)
Visual impairment

What are the existing conditions these people have? *

Breast Cancer Female: 7 people, 36.84%
Metastases To Bone (cancer spreads to bone): 7 people, 36.84%
Pain: 5 people, 26.32%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 15.79%
Stress And Anxiety: 3 people, 15.79%
Nausea (feeling of having an urge to vomit): 3 people, 15.79%
Multiple Myeloma (cancer of the plasma cells): 3 people, 15.79%
High Blood Pressure: 2 people, 10.53%
Anaemia (lack of blood): 2 people, 10.53%
Depression: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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