Hc and Vitamins drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hc (hydrocortisone) and Vitamins (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include irritable bowel syndrome among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Hc and Vitamins. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Hc?

Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.

What is Vitamins?

Vitamins has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 122,456 Vitamins users. Check the latest studies of Vitamins.

On Jul, 28, 2026

59 people who take Hc and Vitamins together, and have interactions are studied.

What are the common drug interactions of Hc and Vitamins, by gender? *:

female:

Irritable bowel syndrome
Osteomalacia (softening of the bones due to a lack of vitamin d)
Polycystic ovaries (cysts in the ovaries that occurs when the follicle stops developing)
Pyrexia (fever)
Sleep disorder
Speech disorder
Temperature intolerance (inability to go in temperature)
Weight increased
Glomerular filtration rate decreased
Somnolence (a state of near-sleep, a strong desire for sleep)

male:

Drug ineffective
Pneumonia
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Pain
Pruritus (severe itching of the skin)
Chronic kidney disease
Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the common drug interactions of Hc and Vitamins, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Alanine aminotransferase increased
Benign breast neoplasm (benign (non-cancerous) tumours of the breast)
Blood bilirubin increased
Blood thyroid stimulating hormone increased
Breast mass
Dizziness
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Joint swelling
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

40-49:

Anxiety
Aphonia (inability to produce voice)
Apnoea (suspension of external breathing)
Blood folate increased
Blood sodium increased
Carbon dioxide decreased
Cardiac disorder
Constipation
Cough
Depression

50-59:

Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Metastases to liver (cancer spreads to liver)
Nerve injury
Rectal abscess (pus in rectum)
Renal cyst (kidney cyst)
Syncope (loss of consciousness with an inability to maintain postural tone)
Temperature intolerance (inability to go in temperature)
Tooth abscess (pus formation in tooth)
Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

60+:

Diarrhoea
Dyspnoea (difficult or laboured respiration)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arthralgia (joint pain)
Asthenia (weakness)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiogenic shock (inadequate circulation of blood)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the existing conditions these people have? *

Pain: 12 people, 20.34%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 11.86%
Immunodeficiency Common Variable: 6 people, 10.17%
High Blood Pressure: 6 people, 10.17%
Migraine (headache): 6 people, 10.17%
Osteoporosis (bones weak and more likely to break): 5 people, 8.47%
Nausea (feeling of having an urge to vomit): 5 people, 8.47%
Drowsiness: 5 people, 8.47%
Depression: 4 people, 6.78%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Hc and Vitamins?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously