Hemlibra and Amicar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hemlibra (emicizumab) and Amicar (aminocaproic acid). Common drug interactions include epistaxis among males.

The phase IV clinical study analyzes what interactions people have when they take Hemlibra and Amicar. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Hemlibra?

Hemlibra has active ingredients of emicizumab. eHealthMe is studying from 6,078 Hemlibra users. Check the latest studies of Hemlibra.

What is Amicar?

Amicar has active ingredients of aminocaproic acid. eHealthMe is studying from 1,323 Amicar users. Check the latest studies of Amicar.



On Aug, 12, 2026

35 people who take Hemlibra and Amicar together, and have interactions are studied.

Hemlibra and Amicar drug interactions.

What are the common drug interactions of Hemlibra and Amicar, by gender? *:

female:

n/a

male:

  1. Epistaxis (bleed from the nose)
  2. Mouth haemorrhage (bleeding from mouth)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Bone density decreased
  6. Depression
  7. Dysstasia (difficulty in standing)
  8. Emotional distress
  9. Gait disturbance
  10. General physical health deterioration (weak health status)

What are the common drug interactions of Hemlibra and Amicar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Epistaxis (bleed from the nose)
  2. Mouth haemorrhage (bleeding from mouth)
  3. Lacrimal haemorrhage (bleeding in lacrimal duct)
  4. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  5. Respiratory disorder (respiratory disease)
  6. Haemorrhage (bleeding)
  7. Tonsillar haemorrhage (bleeding from tonsil)
  8. Arthralgia (joint pain)
  9. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  10. Loose tooth

10-19:

  1. Epistaxis (bleed from the nose)
  2. Arthralgia (joint pain)
  3. Abdominal discomfort
  4. Haemophilic arthropathy (permanent joint disease)
  5. Infection
  6. Muscle haemorrhage (bleeding in muscle)
  7. Post procedural haemorrhage (post procedural bleeding)

20-29:

  1. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  2. Haematuria (presence of blood in urine)
  3. Haemorrhage (bleeding)
  4. Hydronephrosis (water inside the kidney)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Mean cell haemoglobin concentration decreased (less concentration of haemoglobin in a given volume of packed red blood cells)
  7. Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood)
  8. Monocyte percentage increased
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

30-39:

  1. Gingival bleeding (bleeding gums)

40-49:

n/a

50-59:

n/a

60+:

  1. Haemorrhage (bleeding)
  2. Arthralgia (joint pain)
  3. Infusion site pain
  4. Infusion site swelling

What are the existing conditions these people have? *

  1. Mouth Haemorrhage (bleeding from mouth): 3 people, 8.57%
  2. Hiv Infection: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Hemlibra and Amicar?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hemlibra and Amicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hemlibra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hemlibra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amicar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on emicizumab and aminocaproic acid (the active ingredients of Hemlibra and Amicar, respectively), and Hemlibra and Amicar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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