Heparin and Nucala drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Heparin (heparin sodium) and Nucala (mepolizumab). Common drug interactions include gastrointestinal disorder among females and erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Heparin and Nucala. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Heparin?

Heparin has active ingredients of heparin sodium. It is often used in blood clots. eHealthMe is studying from 92,141 Heparin users. Check the latest studies of Heparin.

What is Nucala?

Nucala has active ingredients of mepolizumab. eHealthMe is studying from 26,883 Nucala users. Check the latest studies of Nucala.

On Aug, 01, 2026

58 people who take Heparin and Nucala together, and have interactions are studied.

What are the common drug interactions of Heparin and Nucala, by gender? *:

female:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haematochezia (passage of stools containing blood)
Seasonal allergy (allergic condition due to certain season)
Sensation of foreign body
Sinusitis (inflammation of sinus)
Staphylococcal infection (an infection with staphylococcus bacteria)
Dyspnoea (difficult or laboured respiration)
Nasopharyngitis (inflammation of the nasopharynx)
Asthma
Fall

male:

Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Respiratory tract infection
Cholecystitis infective (infection of gallbladder capable to infect other organs)
Colostomy
Hypertension (high blood pressure)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Upper respiratory tract infection

What are the common drug interactions of Heparin and Nucala, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Renal impairment (severely reduced kidney function)
Arthralgia (joint pain)
Arthropathy
Dyspnoea at rest (difficult or laboured breathing during rest)
Exostosis (formation of new bone on the surface of a bone)
Fluid retention (an abnormal accumulation of fluid in the blood)
Oedema peripheral (superficial swelling)
Pain in extremity
Weight increased
Colitis (inflammation of colon)

60+:

Dyspnoea (difficult or laboured respiration)
Asthma
Depressed mood
Depressive symptom
Dyspnoea exertional (breathlessness or shortness of breath)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Influenza
Injury
Lower respiratory tract infection
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Asthma: 23 people, 39.66%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 11 people, 18.97%
Stable Angina (a constant chest pain): 10 people, 17.24%
Immunodeficiency: 10 people, 17.24%
Immune System Disorder: 10 people, 17.24%
Immunodeficiency Common Variable: 7 people, 12.07%
Dyspnea (difficult or laboured breathing): 6 people, 10.34%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 10.34%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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