Herceptin and Evista drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Herceptin (trastuzumab) and Evista (raloxifene hydrochloride). Common drug interactions include seasonal allergy among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Herceptin and Evista. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Herceptin?

Herceptin has active ingredients of trastuzumab. It is often used in breast cancer. eHealthMe is studying from 42,205 Herceptin users. Check the latest studies of Herceptin.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

On Jul, 05, 2026

38 people who take Herceptin and Evista together, and have interactions are studied.

What are the common drug interactions of Herceptin and Evista, by gender? *:

female:

Seasonal allergy (allergic condition due to certain season)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Tooth disorder (tooth disease)
Tooth impacted (a tooth that fails to fully pass through the gums)
Tricuspid valve incompetence (inefficient heart valve)
Wheezing (a high-pitched whistling sound made while you breath)
Glaucoma (increased fluid pressure in the eye with vision loss)
Death
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Erythema (redness of the skin)

male:

Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Cervicitis (inflammation of the uterine cervix)
Chest pain
Compression fracture (fracture due to pressure caused by injury)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Death
Deformity (disfigurement)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Herceptin and Evista, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Hair disorder

50-59:

Erythema (redness of the skin)
Gingivitis (inflammation of gums)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Hypophagia (reduced food intake)
Injury
Loose tooth
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasal polyps (masses that develop in the lining of the nose)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)

60+:

Diarrhoea
Pain
Dental caries
Fistula (an abnormal connection or passageway between two)
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Malignant neoplasm progression (cancer tumour came back)
Metastases to liver (cancer spreads to liver)
Mitral valve incompetence (inefficient heart valve)
Open wound

What are the existing conditions these people have? *

Osteopenia (a condition where bone mineral density is lower than normal): 18 people, 47.37%
Metastases To Bone (cancer spreads to bone): 18 people, 47.37%
Parkinson's Disease: 15 people, 39.47%
Multiple Myeloma (cancer of the plasma cells): 5 people, 13.16%
High Blood Pressure: 5 people, 13.16%
High Blood Cholesterol: 5 people, 13.16%
Breast Cancer Female: 4 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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