Herceptin and Ribociclib drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Herceptin (trastuzumab) and Ribociclib (ribociclib). Common drug interactions include diarrhoea among females.

The phase IV clinical study analyzes what interactions people have when they take Herceptin and Ribociclib. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Herceptin?

Herceptin has active ingredients of trastuzumab. It is often used in breast cancer. eHealthMe is studying from 42,205 Herceptin users. Check the latest studies of Herceptin.

What is Ribociclib?

Ribociclib has active ingredients of ribociclib. eHealthMe is studying from 1,250 Ribociclib users. Check the latest studies of Ribociclib.



On Jul, 08, 2026

13 people who take Herceptin and Ribociclib together, and have interactions are studied.

Herceptin and Ribociclib drug interactions.

What are the common drug interactions of Herceptin and Ribociclib, by gender? *:

female:

  1. Diarrhoea
  2. Osteonecrosis of jaw (death of bone of jaw)
  3. Pain
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  6. Pneumonia
  7. Nail disorder (disease of nail)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Pyrexia (fever)
  10. Rash

male:

n/a

What are the common drug interactions of Herceptin and Ribociclib, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Rash
  2. Diarrhoea
  3. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  4. Pneumonia
  5. Nail disorder (disease of nail)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Pyrexia (fever)

60+:

  1. Osteonecrosis of jaw (death of bone of jaw)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  4. Pain

What are the existing conditions these people have? *

  1. Rashes (redness): 8 people, 61.54%
  2. Paronychia (infection in the tissues adjacent to a nail on a finger or toe): 8 people, 61.54%
  3. Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 8 people, 61.54%
  4. High Blood Cholesterol: 5 people, 38.46%
  5. Pain: 4 people, 30.77%
  6. Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 30.77%
  7. Gastritis (inflammation of stomach): 4 people, 30.77%
  8. Breast Cancer Metastatic: 4 people, 30.77%
  9. Diarrhea: 3 people, 23.08%
  10. Osteonecrosis Of Jaw (death of bone of jaw): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Herceptin and Ribociclib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Herceptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ribociclib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Herceptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ribociclib and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on trastuzumab and ribociclib (the active ingredients of Herceptin and Ribociclib, respectively), and Herceptin and Ribociclib (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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