Hetlioz and Calcium citrate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hetlioz (tasimelteon) and Calcium citrate (calcium). Common drug interactions include insomnia among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Hetlioz and Calcium citrate. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Hetlioz?
Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.
What is Calcium citrate?
Calcium citrate has active ingredients of calcium. It is often used in osteopenia. eHealthMe is studying from 12,606 Calcium citrate users. Check the latest studies of Calcium citrate.
29 people who take Hetlioz and Calcium citrate together, and have interactions are studied.

What are the common drug interactions of Hetlioz and Calcium Citrate, by gender? *:
female:
- Insomnia (sleeplessness)
- Cough
- Nausea (feeling of having an urge to vomit)
- Headache (pain in head)
- Pain
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Fatigue (feeling of tiredness)
- Oropharyngeal pain
- Dry mouth
- Anxiety
male:
- Drug ineffective
- Insomnia (sleeplessness)
- Sleep talking (talking during sleeping)
- Snoring
- Somnambulism (sleep walking)
- Stress
- Upper-airway cough syndrome
- Hypersomnia (excessive daytime sleepiness (eds))
- Hypnopompic hallucination
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
What are the common drug interactions of Hetlioz and Calcium Citrate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Insomnia (sleeplessness)
- Nausea (feeling of having an urge to vomit)
- Cough
- Fatigue (feeling of tiredness)
- Oropharyngeal pain
- Anxiety
- Viral infection
- Abnormal dreams
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Dizziness
50-59:
- Nausea (feeling of having an urge to vomit)
60+:
- Cough
- Insomnia (sleeplessness)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Fractured sacrum
- Initial insomnia (feeling of inadequate or poor-quality sleep)
- Intervertebral disc protrusion (spinal disc protrusion)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Nightmare (unpleasant dream)
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
- Weight increased
What are the existing conditions these people have? *
- Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 6 people, 20.69%
- Nausea (feeling of having an urge to vomit): 3 people, 10.34%
- Gaze Palsy (disorders affecting the ability to move both eyes in the same direction): 2 people, 6.90%
- Constipation: 2 people, 6.90%
* Approximation only. Some reports may have incomplete information.
Do you take Hetlioz and Calcium citrate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hetlioz (7,418 reports)
- Calcium citrate (12,606 reports)
Browse all drug interactions of Hetlioz and Calcium citrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hetlioz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Calcium citrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hetlioz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Calcium citrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tasimelteon and calcium (the active ingredients of Hetlioz and Calcium citrate, respectively), and Hetlioz and Calcium citrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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