Hetlioz and Oxycodone and acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hetlioz (tasimelteon) and Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride). Common drug interactions include drug ineffective among females and middle insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Hetlioz and Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Hetlioz?

Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

On Jul, 26, 2026

17 people who take Hetlioz and Oxycodone and acetaminophen together, and have interactions are studied.

Hetlioz and Oxycodone and acetaminophen drug interactions.

What are the common drug interactions of Hetlioz and Oxycodone And Acetaminophen, by gender? *:

female:

Drug ineffective
Incontinence (lack of moderation or self-control)
Nightmare (unpleasant dream)
Breast disorder
Headache (pain in head)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)

male:

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Drug ineffective
Quadriparesis (muscle weakness affecting all four limbs)
Tinnitus (a ringing in the ears)
Abnormal dreams
Pneumonia
Fatigue (feeling of tiredness)
Sleep disorder
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased

What are the common drug interactions of Hetlioz and Oxycodone And Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Impatience (restlessness)
Quadriparesis (muscle weakness affecting all four limbs)
Tinnitus (a ringing in the ears)
Drug ineffective
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Insomnia (sleeplessness)
Asthenia (weakness)
Impaired healing

50-59:

Breast disorder
Drug ineffective
Incontinence (lack of moderation or self-control)

60+:

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Abnormal dreams
Drug ineffective
Nightmare (unpleasant dream)

What are the existing conditions these people have? *

Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 6 people, 35.29%

* Approximation only. Some reports may have incomplete information.

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