Hetlioz and Symbicort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hetlioz (tasimelteon) and Symbicort (budesonide; formoterol fumarate dihydrate). Common drug interactions include insomnia among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Hetlioz and Symbicort. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Hetlioz?

Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.

What is Symbicort?

Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. eHealthMe is studying from 114,792 Symbicort users. Check the latest studies of Symbicort.

On Jul, 20, 2026

46 people who take Hetlioz and Symbicort together, and have interactions are studied.

Hetlioz and Symbicort drug interactions.

What are the common drug interactions of Hetlioz and Symbicort, by gender? *:

female:

Insomnia (sleeplessness)
Anxiety
Panic attack
Crying
Poor quality sleep
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Labyrinthitis (inflammation of the labyrinth or inner ear)
Fall
Head injury
Hyperhidrosis (abnormally increased sweating)

male:

Insomnia (sleeplessness)
Drug ineffective
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Disturbance in attention
Dizziness
Malaise (a feeling of general discomfort or uneasiness)
Sleep-related eating disorder (abnormal eating patterns during the night)
Tension (the act or process of stretching something tight)
Toothache (tooth pain)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)

What are the common drug interactions of Hetlioz and Symbicort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Hypersomnia (excessive daytime sleepiness (eds))
Migraine (headache)
Sinusitis (inflammation of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Drug ineffective
Insomnia (sleeplessness)

50-59:

Hyperhidrosis (abnormally increased sweating)
Seasonal allergy (allergic condition due to certain season)
Tinnitus (a ringing in the ears)
Anxiety
Abdominal discomfort
Agitation (state of anxiety or nervous excitement)
Aphonia (inability to produce voice)
Crying
Diarrhoea
Eye disorder

60+:

Drug ineffective
Insomnia (sleeplessness)
Cardiac failure acute
Balance disorder
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Sleep disorder

What are the existing conditions these people have? *

Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 17 people, 36.96%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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