Hetlioz and Zocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hetlioz (tasimelteon) and Zocor (simvastatin). Common drug interactions include drug ineffective among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Hetlioz and Zocor. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Hetlioz?

Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

On Jul, 10, 2026

17 people who take Hetlioz and Zocor together, and have interactions are studied.

What are the common drug interactions of Hetlioz and Zocor, by gender? *:

female:

Drug ineffective
Headache (pain in head)
Insomnia (sleeplessness)
Diarrhoea
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Nightmare (unpleasant dream)
Abdominal pain lower
Abnormal dreams
Affect lability (emotional incontinence)

male:

Insomnia (sleeplessness)
Agitation (state of anxiety or nervous excitement)
Visual impairment
Abnormal dreams
Arthralgia (joint pain)
Chest discomfort
Deafness
Diabetic complication
Drug ineffective
Dry mouth

What are the common drug interactions of Hetlioz and Zocor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chest discomfort

50-59:

Drug ineffective
Abnormal dreams
Affect lability (emotional incontinence)
Dry mouth

60+:

Insomnia (sleeplessness)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Agitation (state of anxiety or nervous excitement)
Arthralgia (joint pain)
Diabetic complication
Drug ineffective
Dry mouth
Dyspnoea (difficult or laboured respiration)
Heart rate increased
Initial insomnia (feeling of inadequate or poor-quality sleep)

What are the existing conditions these people have? *

Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 8 people, 47.06%
Visual Field Defect: 1 person, 5.88%
Sinus Disorder (disease of sinus): 1 person, 5.88%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 5.88%
Nausea (feeling of having an urge to vomit): 1 person, 5.88%
Headache (pain in head): 1 person, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
Dyspnea (difficult or laboured breathing): 1 person, 5.88%
Depression: 1 person, 5.88%
Cardiac Disorder: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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