Humalog kwikpen and Digoxin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Humalog kwikpen (insulin lispro recombinant) and Digoxin (digoxin). Common drug interactions include anaemia among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Humalog kwikpen and Digoxin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Humalog kwikpen?
Humalog kwikpen has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 3,512 Humalog kwikpen users. Check the latest studies of Humalog kwikpen.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
18 people who take Humalog kwikpen and Digoxin together, and have interactions are studied.

What are the common drug interactions of Humalog Kwikpen and Digoxin, by gender? *:
female:
- Anaemia (lack of blood)
- Blood glucose increased
- Blood pressure increased
- Cough
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Influenza
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Nasopharyngitis (inflammation of the nasopharynx)
- Oropharyngeal pain
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Cardiac failure congestive
- Chest pain
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Pulmonary oedema (fluid accumulation in the lungs)
- Staphylococcal infection (an infection with staphylococcus bacteria)
What are the common drug interactions of Humalog Kwikpen and Digoxin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Blood glucose increased
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
60+:
- Ammonia increased
- Death
- Cardiac failure congestive
- Cough
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Influenza
- Nasopharyngitis (inflammation of the nasopharynx)
- Diarrhoea
- Fall
- Hip fracture
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 7 people, 38.89%
- Cardiac Disorder: 3 people, 16.67%
- Gastric Ulcer (stomach ulcer): 3 people, 16.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
- High Blood Pressure: 3 people, 16.67%
- Indigestion: 3 people, 16.67%
- Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 2 people, 11.11%
- Ammonia Increased: 2 people, 11.11%
- Nausea (feeling of having an urge to vomit): 2 people, 11.11%
- Nausea And Vomiting: 2 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Humalog kwikpen and Digoxin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Humalog kwikpen (3,512 reports)
- Digoxin (93,740 reports)
Browse all drug interactions of Humalog kwikpen and Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Humalog kwikpen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Humalog kwikpen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Digoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on insulin lispro recombinant and digoxin (the active ingredients of Humalog kwikpen and Digoxin, respectively), and Humalog kwikpen and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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